Karpova, D., Rettig, M.P., Ritchey, J., (…), Link, D.C., *DiPersio, J.F., The Journal of clinical investigation, 130, 2019.
Li, C., Huang, Z., Gao, N., (…), Niu, H., *Guan, J., ACS Biomaterials Science and Engineering, 5(5), pp. 2173-2179, 2019.
Kirita, Y., Chang-Panesso, M., *Humphreys, B.D., Nephron, 2019.
Kim, M., Huff, E., Bottier, M., (…), *Bayly, P.V., Meacham, J.M., Soft Matter, 15(21), pp. 4266-4275, 2019.
Li, A.S., MacKay, D., Chen, H., Rajagopal, R., *Apte, R.S., Ophthalmology, in press, 2019.
*Guilak, F., *Sandell, L., Huard, J., 2019.
*DiAntonio, A, Pain, 160, pp. S17-S22, 2019.
*Cade, W.T., Bohnert, K.L., Peterson, L.R., (…), Byrne, B.J., Reeds, D.N., Journal of Inherited Metabolic Disease, 42(3), pp. 480-493, 2019.
Mallaney, C., Ostrander, E.L., Celik, H., (…), *Zhang, B., *Challen, G.A, Leukemia, 2019.
Wang, X., Ho, C., Tsatskis, Y., (…), *McNeill, H., Sun, Y., Science Robotics, 4(28), art. no. eaav6180, 2019.
Marín-Hernández, D., Iñiguez, L.P., Nixon, D.F., (…), *DiPersio, J.F., Ley, T.J., New England Journal of Medicine, 380(13), pp. 1289-1290, 2019.
Pita-Thomas, W., Mahar, M., Joshi, A., Gan, D., *Cavalli, V., Experimental Neurology, 317, pp. 271-283, 2019.
Arbouzova, N.I., Fulford, A.D., Zhang, H., *McNeill, H., Developmental Biology, Volume 450, Issue 1, 1 June 2019, Pages 23-33, 2019.
Zhang, H., Bagherie-Lachidan, M., Badouel, C., (…), *Jain, S., *McNeill, H., Developmental Cell, 48(6), pp. 780-792.e4, 2019.
Lahrouchi, N., George, A., Ratbi, I., (…), Brooks, B.P., Sefiani, A., Nature Communications, 10(1), art. no. 1180, 2019.
Lin, J.B., Lin, J.B., Chen, H.C., Chen, T., *Apte, R.S., Scientific Reports, 9(1), art. no. 3799, 2019.
Shin, J.E., Ha, H., Kim, Y.K., Cho, Y., DiAntonio, A., Neurobiology of Disease, 127, pp. 178-192, 2019.
Leimer, E.M., Gayoso, M.G., Jing, L., (…), Gupta, M.C., Setton, L.A., Scientific Reports, 9(1), art. no. 3759, 2019.
Rich Li, a BME student in Stacey Rentschler’s lab, won 1st prize among biomedical engineering students presenting at the WUSTL Graduate Student Senate Research Symposium. Congrats Rich! Other CRM student participants included Kristina Maxwell (Millman Lab), Punn Augsornworawat (Millman Lab), and Bisi Fashemi (Mysorekar Lab).
Lin, J.B., *Apte, R.S. Immunity, 50:544-46, 2019.
Kabir, A.U., Lee, T.-J., Pan, H., (…), Miller, M.J., Choi, K. JCI Insight, 3, 2018.
Li, C., Huang, Z., Gao, N., Zheng, J., *Guan, J. Materials Science and Engineering C, 99: 1191-1198, 2019.
Research from Dr. Jianjun Guan (MEMS) was featured in the Feb 25 issue of The Record. Dr. Guan and his team are developing novel biomaterials to directly deliver therapies to the infarcted heart.
*Geisler, S., Huang, S.X., Strickland, A., (…), *DiAntonio, A., *Milbrandt, J. J Exp Med, 216(2), pp. 294-303, 2019.
Gilchrist, C.L., Leddy, H.A., Kaye, L., (…), Hoffman, B.D., *Guilak, F. PNAS U S A, 116(6), pp. 1992-1997, 2019.
Suzuki-Hatano, S., Saha, M., Rizzo, S.A., (…), *Cade, W.T., Pacak, C.A. Human Gene Therapy, 30(2), pp. 139-154, 2019.
Suzuki-Hatano, S., Saha, M., Soustek, M.S., (…), Cade, W.T., Pacak, C.A. Molecular Therapy – Methods and Clinical Development, 13, pp. 167-179, 2019.
Russo, A., Goel, P., Brace, E.J., (…), Dickman, D., DiAntonio, A. The E3 ligase Highwire promotes synaptic transmission by targeting the NAD-synthesizing enzyme dNmnat. EMBO Rep, art. e46975, 2019.
Dr. John DiPersio (Department of Medicine, Chief, Division of Oncology) will lead the first US Phase I/II clinical trial for ApoGraf, a stem cell selection technology developed by Cellect Biotechnology. ApoGraf is designed to prevent acute Graft vs. Host Disease following bone marrow transplant.
Apte, R.S., Chen, D.S., Ferrara, N. VEGF in Signaling and Disease: Beyond Discovery and Development. Cell, 2019.
Harasymowicz, N.S., Dicks, A., Wu, C.-L., Guilak, F. Physiologic and pathologic effects of dietary free fatty acids on cells of the joint. Annals New York Acad Sci, 2019.
Regis O’Keefe MD, PhD (Professor and Head of Orthopedic Surgery) was honored with the Alfred R. Shands, Jr, MD Award at the 2019 meeting of the Orthopedic Research Society. This award is presented to a United States or Canadian citizen who has made significant contributions to orthopaedics. This award recognizes the devotion of a significant […]
Rai, M.F., Sandell, L.J., Barrack, T.N., (…), Silva, M.J., Barrack, R.L. A Microarray Study of Articular Cartilage in Relation to Obesity and Severity of Knee Osteoarthritis. Cartilage, 2018.
Wilson, P.C., Humphreys, B.D. Single-cell genomics and gene editing: implications for nephrology. Nat Rev Nephrol, 2018.
Qu, F., Guilak, F., Mauck, R.L. Cell migration: implications for repair and regeneration in joint disease. Nat Rev Rheumatol, 2019.
Ornitz, D.M., Marie, P.J. Fibroblast growth factors in skeletal development. Curr Opin Dev Biol, 2019.
Oh, Y.M., Mahar, M., Ewan, E.E., (…), Zhao, G., Cavalli, V. Epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration. PNAS, 115:E12417-26, 2018.
David Ornitz, Alumni Endowed Professor of Developmental Biology, was named a Fellow of the American Association of Anatomists, an honor designed to recognize distinguished members who have demonstrated excellence in science and in their overall contributions to the anatomical sciences.
On January 9th, the Center of Regenerative Medicine celebrated the successes of some of our faculty members. Promotion to associate professor with tenure (Grant Challen, Medicine; Spencer Lake, Mechanical Engineering; Andrew Yoo, Developmental Biology), promotion to full professor (Indira Mysorekar, Ob/Gyn), fellowship in the AAAS (Lila Solnica-Krezel, Developmental Biology and Deborah Rubin, Medicine), and installation […]
Aaron DiAntonio and Jeff Milbrant recently demonstrated the power of blocking the SARM1 pathway for preventing nerve degeneration. Building on previous work, they used adeno-associated virus to deliver a dominant-negative form of the SARM1 protein to mice. When axons in these mice were injured, they were resistant to degeneration. These studies have implications for many […]
In a paper recently published in the inaugural issue of Nature Metabolism, Shin Imai’s lab reported on the identity of the NMN transporter, a key molecule with implications for aging.
Wu, H., Uchimura, K., Donnelly, E.L., (…), Morris, S.A., Humphreys, B.D. Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics. Cell Stem Cell, 23:869-81, 2018.
Venkatesan, J.K., Moutos, F.T., Rey-Rico, A., (…), Guilak, F., Cucchiarini, M. Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(∈-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer. Human Gene Ther, 29:1277-86, 2018.
Rai, M.F., Brophy, R.H., Sandell, L.J. Osteoarthritis following meniscus and ligament injury: insights from translational studies and animal models. Curr Opin Rheumatol, 31:70-79, 2019.
Alahmari, B., Cooper, M., Ziga, E., (…), DiPersio, J.F., Choi, J. Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation. PLoS One, 13, p.e0207609, 2018.
Johnson, S., Wozniak, D.F., Imai, S. CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves.npj Aging and Mechanisms of Disease, 4(1), art. no. 10, 2018.
Adkar, S.S., Wu, C.-L., Willard, V.P., (…), Gersbach, C.A., Guilak, F. Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing. Stem Cells, 37:65-76, 2019.
Celik, H., Koh, W.K., Kramer, A.C., (…), Oh, S.T., Challen, G.A. JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells. Cancer Cell 34:741-756.e8, 2018.
Lu Yang (PhD student), Sung-Ho Huh (former postdoc), and David Ornitz (PI) are among the winners of the 2018 FASEB BioArt competition for their stunning image of the olfactory epithelium within the mouse nasal cavity. The Ornitz Lab also won in 2017 for their X-ray microscopy study showing blood flow in the lungs. Congrats!
Adkar SS, Wu C-L, Willard VP, Dicks A, Ettyreddy A, Steward N, Bhutani N, Gersbach CA, Guilak F. Step‐Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR‐Cas9 Genome Editing. Stem Cells, online, 2018.