Tung, T.H., *Mackinnon, S.E. Curr Opin Organ Transplant 23:577-81, 2019.
Category: Publications
Congenital lipodystrophy induces severe osteosclerosis (Links to an external site)
Zou, W., Rohatgi, N., Brestoff, J.R., (…), *Silva, M.J., Harris, C.A., *Teitelbaum, S.L. PLoS Genetics, 15:e1008244, 2019.
The evolving concept of cell identity in the single cell era (Links to an external site)
*Morris, SA. Development, 146, 2019.
Distinct expression pattern of periostin splice variants in chondrocytes and ligament progenitor cells (Links to an external site)
Cai, L., Brophy, R.H., Tycksen, E.D., (…), Nunley, R.M., *Rai, M.F. FASEB J, 33:8386-405, 2019.
Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia (Links to an external site)
Carlin, D., Halevi, A.E., Ewan, E.E., Moore, A.M., Cavalli, V. eNeuro, 6, 2019.
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages (Links to an external site)
Saunders, L.M., Mishra, A.K., Aman, A.J., (…), Corbo, J.C.,* Trapnell, C., Parichy, D.M. eLife, 8:e45181, 2019.
Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome (Links to an external site)
Park, S.-J., Kim, Y., Yang, S.-M., (…), *Urano, F., Chen, Y.M. Proc Nat Acad Sci U S A, 116:14154-14163, 2019.
Lack of fractalkine receptor on macrophages impairs spontaneous recovery of ribbon synapses after moderate noise trauma in c57bl/6 mice (Links to an external site)
Kaur, T., Clayman, A.C., Nash, A.J., (…), *Warchol, M.E., Ohlemiller, K.K. Frontiers in Neuroscience, 13, art. no. 620, 2019.
miR-892b Inhibits Hypertrophy by Targeting KLF10 in the Chondrogenesis of Mesenchymal Stem Cells (Links to an external site)
Lee, J.M., Ko, J.-Y., Kim, H.Y., (…), *Guilak, F., Im, G.-I. Molecular Therapy – Nucleic Acids, 17:310-322, 2019.
Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts (Links to an external site)
Hegab, A.E., Ozaki, M., Kameyama, N., (…), *Ornitz, D.M., Betsuyaku, T. J Pathol, 2019.
FeatSNP: An interactive database for brain-specific epigenetic annotation of human SNPs
Ma, C.-Y., Madden, P., *Gontarz, P., *Wang, T., *Zhang, B. Frontiers in Genetics, 10, art. no. 262, 2019.
Insights into traumatic brain injury from MRI of harmonic brain motion (Links to an external site)
Okamoto, R.J., Romano, A.J., Johnson, C.L., *Bayly, P.V. J Exp Neurosci, 13, 2019.
Osteocyte Death and Bone Overgrowth in Mice Lacking Fibroblast Growth Factor Receptors 1 and 2 in Mature Osteoblasts and Osteocytes (Links to an external site)
McKenzie, J., Smith, C., Karuppaiah, K., (…), *Silva, M.J., *Ornitz, D.M. J Bone Min Res, 2019.
DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs (Links to an external site)
Bayer, S.V., Grither, W.R., Brenot, A., (…), *Pathak, A., Longmore, G.D. eLife, 8, 2019.
Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets (Links to an external site)
Emfinger, C.H., Lőrincz, R., Wang, Y., (…), *Remedi, M.S., Nichols, C.G. Physiological Reports, 7(11), art. no. e14101, 2019.
Interactions between macrophages and the sensory cells of the inner ear (Links to an external site)
*Warchol, ME. Cold Spring Harbor Perspectives in Medicine,9, a033555, 2019.
Neuroma Management: Capping Nerve Injuries With an Acellular Nerve Allograft Can Limit Axon Regeneration (Links to an external site)
Hong, T., Wood, I., Hunter, D.A., (…), *Wood, M.D., Moore, A.M. Hand, 2019.
Paper from Humphreys & Morris labs featured in ‘The Best of Cell Stem Cell 2018’ (Links to an external site)
The recent collaborative paper from the Humphreys and Morris labs, titled ‘Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics’ was featured in ‘The Best of Cell Stem Cell 2018.’ The most-highly accessed papers of 2018 were included in this special issue. Congrats to everyone on the team!
The accumulation of T cells within acellular nerve allografts is length-dependent and critical for nerve regeneration (Links to an external site)
Pan, D., Hunter, D.A., Schellhardt, L., (…), *Mackinnon, S.E., *Wood, M.D., Experimental Neurology, 318, pp. 216-231, 2019.
Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells (Links to an external site)
Karpova, D., Rettig, M.P., Ritchey, J., (…), Link, D.C., *DiPersio, J.F., The Journal of clinical investigation, 130, 2019.
Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species (Links to an external site)
Stein-O’Brien, G.L., Clark, B.S., Sherman, T., (…), Goff, L.A., Fertig, E.J., Cell Systems, Volume 8, Issue 5, 22 May 2019, Pages 395-411.e8, 2019.
CellTag Indexing: Genetic barcode-based sample multiplexing for single-cell genomics (Links to an external site)
Guo, C., Kong, W., Kamimoto, K., (…), Kirita, Y., *Morris, S.A., Genome Biology, 20(1), art. no. 90, 2019.
Engineering Tissues from Induced Pluripotent Stem Cells (Links to an external site)
Loskill, P., *Huebsch, N., Tissue Engineering – Part A, 25(9-10), pp. 707-710, 2019.
Trauma induces emergency hematopoiesis through IL-1/MyD88–dependent production of G-CSF (Links to an external site)
Fuchs, A., Monlish, D.A., Ghosh, S., (…), *Schuettpelz, L.G., Turnbull, I.R., Journal of immunology, 202(10), pp. 3020-3032, 2019.
Injectable Oxygen Sensitive Chitosan Complex with High Oxygen Sensitivity and Stability to Oxidoreductants (Links to an external site)
Li, C., Huang, Z., Gao, N., (…), Niu, H., *Guan, J., ACS Biomaterials Science and Engineering, 5(5), pp. 2173-2179, 2019.
Recent Insights into Kidney Injury and Repair from Transcriptomic Analyses (Links to an external site)
Kirita, Y., Chang-Panesso, M., *Humphreys, B.D., Nephron, 2019.
Fat-Produced Adipsin Regulates Inflammatory Arthritis (Links to an external site)
Li, Y., Zou, W., Brestoff, J.R., (…), Harris, C.A., *Teitelbaum, S.L., Cell Reports, 27(10), pp. 2809-2816.e3, 2019.
Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival (Links to an external site)
Murphy, J.T., Liu, H., Ma, X., (…), Kornfeld, K., *Diwan, A., PLoS biology, 17(5), p. e3000245, 2019.
Acoustic trap-and-release for rapid assessment of cell motility (Links to an external site)
Kim, M., Huff, E., Bottier, M., (…), *Bayly, P.V., Meacham, J.M., Soft Matter, 15(21), pp. 4266-4275, 2019.
Translational mechanobiology: Designing synthetic hydrogel matrices for improved in vitro models and cell-based therapies (Links to an external site)
*Huebsch, N, Acta Biomaterialia, 2019.
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms (Links to an external site)
Li, P., Marshall, L., Oh, G., (…), Petronis, A., Labrie, V., Nature Communications, 10(1), art. no. 2246, 2019.
Challenges to Routine Genetic Testing for Inherited Rod Dystrophies (Links to an external site)
Li, A.S., MacKay, D., Chen, H., Rajagopal, R., *Apte, R.S., Ophthalmology, in press, 2019.
Journal of Orthopaedic Research: Special Issue on Stem Cells (Links to an external site)
*Guilak, F., *Sandell, L., Huard, J., 2019.
Computational Tool to Study Perturbations in Muscle Regulation and Its Application to Heart Disease (Links to an external site)
Barrick, S.K., Clippinger, S.R., Greenberg, L., Greenberg, M.J., Biophysical J, online, 2019.
Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity (Links to an external site)
Jarjour, N.N., Schwarzkopf, E.A., Bradstreet, T.R., (…), Urban, J.F., Edelson, B.T., Nature Immunology, Volume 20, Issue 6, 1 June 2019, Pages 687-700, 2019.
The role of membrane excitability in pancreatic β-cell glucotoxicity (Links to an external site)
Shyr, Z.A., Wang, Z., York, N.W., Nichols, C.G., Remedi, M.S., Scientific Reports, 9(1), art. no. 6952, 2019.
Rapid population-wide declines in stem cell number and activity during reproductive aging in C. elegans (Links to an external site)
Kocsisova, Z., Kornfeld, K., Schedl, T., Development, 146(8), 2019.
Axon degeneration: mechanistic insights lead to therapeutic opportunities for the prevention and treatment of peripheral neuropathy (Links to an external site)
*DiAntonio, A, Pain, 160, pp. S17-S22, 2019.
Lithium chloride corrects weakness and myopathology in a preclinical model of LGMD1D (Links to an external site)
Findlay, A.R., Bengoechea, R., Pittman, S.K., (…), True, H.L., *Weihl, C.C., Neurology: Genetics, 5(2), art. no. e318, 2019.
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs (Links to an external site)
Pontis, J., Planet, E., Offner, S., (…), Jaenisch, R., Trono, D., Cell Stem Cell, 24(5), pp. 724-735.e5, 2019.
Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome (Links to an external site)
*Cade, W.T., Bohnert, K.L., Peterson, L.R., (…), Byrne, B.J., Reeds, D.N., Journal of Inherited Metabolic Disease, 42(3), pp. 480-493, 2019.
Calcified, top secretion only: epithelial repair in gastric organoids requires calcium mobilization (Links to an external site)
Cho, C.J., Mills, J.C., Journal of Physiology, Volume 597, Issue 10, 15 May 2019, Pages 2617-2618, 2019.
Decreased lysyl oxidase level protects against development of retinal vascular lesions in diabetic retinopathy (Links to an external site)
Kim, D., *Mecham, R.P., Nguyen, N.-H., Roy, S., Experimental Eye Research, 184, pp. 221-226, 2019.
Atg14 protects the intestinal epithelium from TNF-triggered villus atrophy (Links to an external site)
Jung, H., Leal-Ekman, J.S., Lu, Q., *Stappenbeck, T.S., Autophagy, online, 2019.
Phenotype and response to growth hormone therapy in siblings with B4GALT7 deficiency (Links to an external site)
Sandler-Wilson, C., Wambach, J.A., Marshall, B.A., (…), *Cole, F.S., Shinawi, M., Bone, 124, pp. 14-21, 2019.
Transposable elements drive widespread expression of oncogenes in human cancer (Links to an external site)
Jang, H.S., Shah, N.M., Du, A.Y., (…), Gordon, J.I., *Wang, T., Nature Genetics, 51(4), pp. 611-617, 2019.
L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams (Links to an external site)
VanDussen, K.L., Sonnek, N.M., *Stappenbeck, T.S., Stem Cell Research, 37, art. no. 101430, 2019.
Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells (Links to an external site)
Stone, S., Abreu, D., Mahadevan, J., (…), Hershey, T., *Urano, F., Scientific Reports, 9(1), art. no. 5199, 2019.
Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita (Links to an external site)
Fok, W.C., Shukla, S., Vessoni, A.T., (…), *Sturgeon, C.M., *Batista, L.F.Z., Blood, 133(12), pp. 1308-1312, 2019.
Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis (Links to an external site)
Mallaney, C., Ostrander, E.L., Celik, H., (…), *Zhang, B., *Challen, G.A, Leukemia, 2019.