Peggy Kendall, MD

Peggy Kendall, MD

Professor and Chief, Division of Allergy and Immunology, Department of Medicine

The Kendall Lab works on B Lymphocyte tolerance in autoimmune diseases, including Rheumatoid arthritis, Type 1 diabetes, and Systemic sclerosis. They also study allergic diseases, including food allergy.

Kendall Lab website »

Albert Kim, MD, PhD

Albert Kim, MD, PhD

Professor, Neurosurgery

The Kim Lab studies the cell-intrinsic molecular mechanisms governing brain cancer stem cell function, normal nervous system development, and the development of clinical surgical protocols to deliver cell-based and drug therapies for a variety of nervous system disorders.

 

Kim Lab website »

Miriam Kim

Miriam Kim

Assistant Professor, Oncology

Focused research on rational manipulation of human hematopoietic cells for the treatment of disease by combining genetically engineered hematopoietic stem cells and chimeric antigen receptor T cells for therapy of acute myeloid leukemia.

Faculty Profile »

Kristen Kroll, PhD

Kristen Kroll, PhD

Professor, Developmental Biology

The Kroll lab studies the epigenetic and transcriptional regulators that control fate decisions from embryonic stem cells into the neural lineage.

 

Kroll Lab website »

Spencer Lake, PhD

Spencer Lake, PhD

Associate Professor, Mechanical Engineering and Materials Science

The Lake lab studies the biomechanics and structure-function relationships of soft tissues and how these change in injury and disease.

 

Lake Lab website »

Kory Lavine, MD, PhD

Kory Lavine, MD, PhD

Associate Professor, Division of Cardiology, Department of Medicine

The Lavine lab studies heart development and the role of macrophages in cardiac recovery and reprogramming.

 

Lavine Lab website »

Jin-Moo Lee, MD, PhD

Jin-Moo Lee, MD, PhD

Andrew B & Gretchen P Jones Professor. Chairman, Department of Neurology

The Lee Lab is engaged in translational research to investigate cellular and molecular mechanisms involved in acute and chronic brain injury, with a focus on ischemic stroke and Alzheimer’s disease.  An additional focus of the lab is neuroplasticity and brain repair after stroke.  A major motivation of the lab is to identify strategies and targets for mitigating brain injury and enhancing brain repair after injury. 

Lee Lab website »

Tristan Qingyun Li, PhD

Tristan Qingyun Li, PhD

Assistant Professor, Departments of Neuroscience and Genetics

The Li lab is broadly interested in neuroimmunology with a focus on microglial biology. They combine cutting-edge single-cell genomic technologies with in vitro and in vivo genetic, molecular, and cellular tools to address these fundamental questions, which also have tremendous translational potential. The overarching goal is to gain a better understanding of microglial functions in the establishment of the nervous system, as well as how changes in these functions contribute to aging and neurological diseases.

Li Lab website »

Xiaowei Li, PhD

Xiaowei Li, PhD

Assistant Professor, Department of Surgery, Division of Plastic Surgery

The Li lab is developing biomaterials platforms for regenerative medicine, with specific interest in applications of biomaterials for angiogenesis and vascularization, stem cell engineering, and central nervous system and soft tissue regeneration.

Li Lab website »

Susan Mackinnon, MD

Susan Mackinnon, MD

Sydney M. Jr. and Robert H. Shoenberg Professor and Chief, Division of Plastic and Reconstructive Surgery, Department of Surgery

The Mackinnon lab studies peripheral nerve allotransplantation and the effect of GDNF on nerve regeneration.

 

Faculty profile »

Audrey McAlinden, PhD

Audrey McAlinden, PhD

Associate Professor, Orthopedic Surgery

The McAlinden lab studies the molecular mechanisms regulating cartilage development and maintenance.

 

McAlinden Lab website »

Helen McNeill, PhD

Helen McNeill, PhD

Barnes Jewish Investigator and Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor of Developmental Biology

The McNeill Lab works on the roles of Fat cadherins in growth and regeneration, using Drosophila, mouse, and hydra.

 

McNeill Lab website »

Robert Mecham, PhD

Robert Mecham, PhD

Alumni Endowed Professor of Cell Biology and Physiology

The Mecham Lab studies how the extracellular matrix influences tissue development and regulates growth factor signaling.

 

Mecham Lab website »

Michael Meers, PhD

Michael Meers, PhD

Assistant Professor, Department of Genetics

The Meers Lab studies how transcription factors interact with and overcome barriers presented by chromatin landscapes to specify developmental and cellular reprogramming outcomes. To do so, we develop cutting-edge epigenomics techniques to map transcription factor binding and chromatin structure in the same context at high resolution.
Isabel Menendez, DVM, PhD

Isabel Menendez, DVM, PhD

Assistant Professor of Orthopedic Surgery

Dr. Menendez uses preclinical multimodal imaging technologies for biomarker discovery in orthopedic diseases.

Faculty profile website »

Gretchen Meyer, PhD

Gretchen Meyer, PhD

Assistant Professor, Physical Therapy

The Meyer lab studies the effects of muscle injury at the molecular and tissue level and the role of adipose tissue in muscle repair.

 

Faculty profile »

Craig Micchelli, PhD

Craig Micchelli, PhD

Associate Professor, Developmental Biology

The Micchelli lab investigates the molecular mechanisms controlling Drosophila stem cell fate decisions, and how these can inform our understanding of all stem cell systems.

 

Faculty profile »

Jeffrey Milbrandt, MD, PhD

Jeffrey Milbrandt, MD, PhD

James S. McDonnell Professor and Head of Genetics

The Milbrandt lab studies mechanisms that influence axonal degeneration and regeneration.

 

Milbrandt Lab website »

Timothy Miller, MD, PhD

Timothy Miller, MD, PhD

The David Clayson Professor of Neurology

The Miller lab aims to understand the mechanisms underlying neurodegeneration and to develop novel therapies for neurodegenerative diseases, especially ALS.

 

Miller Lab website »

Jeffrey Millman, PhD

Jeffrey Millman, PhD

Associate Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine

The Millman lab investigates novel stem cell technology and biomedical engineering approaches for the treatment of diabetes.

 

Millman Lab website »

Sumegha Mitra, MS, PhD

Sumegha Mitra, MS, PhD

Associate Professor of Obstetrics and Gynecology

Dr. Mitra is focused on chemotherapy stress-induced mechanisms that provide resistance to endoplasmic reticulum stress and promote cell survival. She is also interested in regulating protein homeostasis to re-sensitize chemoresistant ovarian cancer to platinum drugs.

Mitra Lab website »

Mayssa Mokalled, PhD

Mayssa Mokalled, PhD

Assistant Professor, Developmental Biology

The Mokalled lab investigates mechanisms of spinal cord regeneration after injury or disease using zebrafish as a primary model.

 

Mokalled Lab website »

Josh Morgan, PhD

Josh Morgan, PhD

Assistant Professor of Ophthalmology

The Morgan Lab studies the organization, development, degeneration, and regeneration of the synaptic organization of the visual system. We are currently focused on determining the extent to which microcircuitry in the visual thalamus can recover from denervation..

Morgan Lab website »

Samantha Morris, PhD

Samantha Morris, PhD

Associate Professor of Genetics and of Developmental Biology

The Morris lab studies the gene regulatory networks that define cell fate. This information is applied to engineer cell identity, and to better understand cell fate decisions in development and disease.

 

Morris Lab website »

Jeffrey Neil, MD, PhD

Jeffrey Neil, MD, PhD

Professor, Department of Neurology

The Neil lab specializes in the use of MRI methods to evaluate brain development in animal models and human infants.

Neil Lab website »

Jeanne Nerbonne, PhD

Jeanne Nerbonne, PhD

Alumni Endowed Professor of Developmental Biology and of Medicine, Division of Cardiology

The Nerbonne lab studies the molecular mechanisms controlling the properties, the cell surface expression, and the function of voltage (K+) gated channels in the cardiovascular and nervous systems.

 

Nerbonne Lab website »

Regis O'Keefe, MD, PhD

Regis O'Keefe, MD, PhD

Fred C. Reynolds Professor and Head of Orthopedic Surgery

The O’Keefe lab studies skeletal development and repair, cancer, and inflammatory diseases of bone.

 

O'Keefe Lab website »

Arin Oestreich

Arin Oestreich

Assistant Professor of Orthopaedic Surgery

Dr. Oestreich's research focuses on how maternal obesity influences pregnancy health, fetal skeletal development, and the long term metabolic and musculoskeletal health of the adult offspring.

Faculty profile website »

John A Olson Jr, MD, PhD

John A Olson Jr, MD, PhD

Chair, Department of Surgery, William K. Bixby Professor

The Olson laboratory investigates the molecular pathogenesis of parathyroid tumors with additional interests in parathyroid regeneration and transplantation. Clinical research within the Olson lab has focused on novel neoadjuvant therapies for breast cancer and biomarkers of breast cancer clinical outcomes.

Olson Lab website »

David Ornitz, MD, PhD

David Ornitz, MD, PhD

Alumni Endowed Professor of Developmental Biology

The Ornitz lab investigates the functions of Fibroblast Growth Factors (FGFs), their interactions with other signaling pathways, and their role in tissue regeneration, response to injury, and cancer.

 

Ornitz Lab website »

Michelle Oyen, PhD

Michelle Oyen, PhD

Associate Professor, Biomedical Engineering

Research in the Oyen Lab is focused on pregnancy and women's health research, particularly in engineering approaches for prevention of and intervention into preterm birth.

 

Oyen Lab website »

B. Duygu Ozpolat, PhD

B. Duygu Ozpolat, PhD

Assistant Professor, Department of Biology

If humans lose their reproductive cells (i.e eggs and sperm) they become infertile, in contrast, some animals regenerate their reproductive cells and reproductive organs. The Ozpolat lab's goal is to uncover the mechanisms of reproductive cell and tissue regeneration by identifying the cell types and genes involved in this process, which will inform regenerative medicine approaches.

Ozpolat lab website »

Hua Pan, PhD

Hua Pan, PhD

Associate Professor, Department of Medicine

The Pan Lab is studying the basic conception, development, and clinical application of novel nanostructures that serve as safe and effective delivery vehicles for therapeutic nucleotides to mitigate diseases including arthritis and cancer treatment induced vital organ injury.

Pan Lab website »

Randal Paniello, MD, PhD

Randal Paniello, MD, PhD

Professor, Otolaryngology

The Paniello lab is interested in using muscle stem cells to repair and treat vocal cord paralysis.

 

Paniello Lab website »

Rohit Pappu, PhD

Rohit Pappu, PhD

Gene K. Beare Distinguished Professor of Biomedical Engineering

The Pappu Lab studies the molecular basis of neurodegeneration, phase transitions that lead to protein and RNA condensates driven by multivalent molecules, the biophysics of intrinsically disordered proteins, and design of responsive, protein-based biomaterials. This includes multiscale computer simulations, adaptations and developments of polymer physics theories, in vitro experiments, and collaborations that enable molecular and cellular level investigations.

Pappu Lab website »

Cecilia Pascual-Garrido, MD

Cecilia Pascual-Garrido, MD

Assistant Professor, Orthopedic Surgery

Dr. Pascual-Garrido’s lab focuses on stem cell therapies for cartilage regeneration.

 

Pascual-Garrdio Lab website »

Amit Pathak, PhD

Amit Pathak, PhD

Associate Professor, Mechanical Engineering and Materials Science

The Pathak lab uses a multidisciplinary approach combining methods and concepts from biomaterials, microfluidics, molecular and cell biology, microscopy, applied mechanics, and computational modeling to investigate the ability of living cells to move through complex tissue environments.

 

Pathak Lab website »

Debabrata Patra, PhD

Debabrata Patra, PhD

Associate Professor, Orthopedic Surgery

The Patra lab is interested in identifying and analyzing regulatory pathways that impact skeletal development. In particular, the lab is exploring roles for the proprotein convertase Site-1 protease (S1P) in cartilage, bone, and spine development.

Christine Pham, MD

Christine Pham, MD

Guy and Ella Mae Magness Professor of Medicine and Chief of Division of Rheumatology

The Pham lab focuses on understanding the contribution of innate immunity to inflammatory and rheumatic diseases. They also develop nanomedicine and regenerative medicine approaches for the treatment of arthritis.

 

Faculty profile »

M. Farooq Rai, PhD

M. Farooq Rai, PhD

Assistant Professor, Department of Orthopedic Surgery

Dr. Rai is interested in understanding the early molecular mechanisms that orchestrate changes in knee joint after injury and lead to the development of post-traumatic osteoarthritis.

Gwendalyn Randolph, PhD

Gwendalyn Randolph, PhD

Professor, Pathology and Immunology

The Randolph Lab studies the development and diseases associated with monocytes, monocyte-derived cells, dendritic cells and vascular and lymphatic vessel biology.

 

Randolph Lab website »

Michael Rauchman, MDCM

Michael Rauchman, MDCM

Professor, Division of Nephrology, Department of Medicine

Dr. Rauchman’s research focuses on understanding the molecular and genetic basis of mammalian kidney development, how disruption of specific pathways leads to abnormal development of this organ, the consequences of injury to adult kidney and the relationship between genetic mutations in humans and the development of future cardiovascular and renal disorders in humans.

 

Faculty profile »

Maria Remedi, PhD

Maria Remedi, PhD

Assistant Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine

The major focus of the Remedi laboratory is to study in vivo physiology in various mouse models of diabetes to unravel the underlying mechanisms of pancreatic β-cell failure and their consequences in both pancreatic and extra-pancreatic tissues.

 

Remedi Lab website »

Stacey Rentschler, MD, PhD

Stacey Rentschler, MD, PhD

Associate Professor, Division of Cardiology, Department of Medicine

The Rentschler lab studies the molecular mechanisms of conduction cell specification and conductive disorders in heart biology.

 

Faculty profile »

Deborah  Rubin, MD

Deborah Rubin, MD

William B. Kountz Professor of Medicine, Division of Gastroenterology, Department of Medicine

The Rubin lab studies the molecular mechanisms underlying the regulation of intestinal epithelial cell proliferation, differentiation, and carcinogenesis.

 

Faculty profile »

David Rudnick, PhD

David Rudnick, PhD

Associate Professor, Pediatrics

The Rudnick lab seeks to gain an understanding of liver regeneration to improve the treatment of children with liver disease.

 

Faculty profile »

Alexandra  Rutz, PhD

Alexandra Rutz, PhD

Assistant Professor, Biomedical Engineering

The Rutz lab is focused on bridging living systems and technologies through the design of materials and development of advanced manufacturing methods.

 

Rutz Lab »

Mark Sands, PhD

Mark Sands, PhD

Professor, Division of Oncology, Department of Medicine

The Sands lab studies the underlying pathophysiology of lysosomal storage diseases and develops therapies to treat them.

 

Faculty profile »

Timothy Schedl, PhD

Timothy Schedl, PhD

Professor, Genetics

The Schedl lab investigates how stem cells choose between self renewal and differentiation and how sex determination is controlled.

 

Schedl Lab website »

Erica L Scheller, DDS, PhD

Erica L Scheller, DDS, PhD

Executive Director, Center of Regenerative Medicine; Associate Professor of Medicine; Associate Professor of Cell Biology and Physiology

The Scheller laboratory synthesizes concepts from cell biology, physiology, and bioengineering to study the relationships between the nervous system and the skeleton. They have a directed interest in understanding how neural signals contribute to skeletal homeostasis, and how perturbations to this system contribute to bone loss, impaired healing, and altered regeneration. They also seek to understand how skeletal cells and proteins coordinate and regulate nerve regeneration in and on the bone.

Scheller Lab website »