A virtual symposium on FGFR syndromes is planned for March 17-18, 2022. Dave Ornitz, who is a member of the Born a Hero Medical Advisory Board, will be presenting.
Identification of a FGF18-expressing alveolar myofibroblast that is developmentally cleared during alveologenesis (Links to an external site)
Hagan, A.S., *Zhang, B., *Ornitz, D.M. Development,Volume 147: Article number dev181032, 2020.
Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes (Links to an external site)
Meyer, M., Ben-Yehuda Greenwald, M., Rauschendorfer, T., (…), *Ornitz, D.M., Werner, S. Journal of Cellular and Molecular Medicine,Volume 24: 1774-1785, 2019.
β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea (Links to an external site)
Jansson, L., Ebeid, M., Shen, J.W., (…), Huh, S.-H., Cheng, A.G. PNAS, 116(42), pp. 21054-21060, 2019.
FGF2-induced STAT3 activation regulates pathologic neovascularization (Links to an external site)
Dong, Z., Santeford, A., Ban, N., (…), *Ornitz, D.M., *Apte, R.S. Experimental Eye Research, 187, art. no. 107775, 2019.
Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner (Links to an external site)
Yang, L.M., Cheah, K.S.E., Huh, S.-H., *Ornitz, D.M., PLoS Genetics, Volume 15, Issue 7, July 2019, Article number e1008254, 2019.
Generation and validation of novel conditional flox and inducible Cre alleles targeting fibroblast growth factor 18 (Fgf18) (Links to an external site)
Hagan, A.S., Boylan, M., Smith, C., (…), Lewandoski, M., Ornitz, D.M. Dev Dyn, 2019.
Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts (Links to an external site)
Hegab, A.E., Ozaki, M., Kameyama, N., (…), *Ornitz, D.M., Betsuyaku, T. J Pathol, 2019.
Osteocyte Death and Bone Overgrowth in Mice Lacking Fibroblast Growth Factor Receptors 1 and 2 in Mature Osteoblasts and Osteocytes (Links to an external site)
McKenzie, J., Smith, C., Karuppaiah, K., (…), *Silva, M.J., *Ornitz, D.M. J Bone Min Res, 2019.
Review article from the Ornitz Lab (Links to an external site)
Ornitz, D.M., Marie, P.J. Fibroblast growth factors in skeletal development. Curr Opin Dev Biol, 2019.
David Ornitz named a Fellow of American Association of Anatomists (Links to an external site)
David Ornitz, Alumni Endowed Professor of Developmental Biology, was named a Fellow of the American Association of Anatomists, an honor designed to recognize distinguished members who have demonstrated excellence in science and in their overall contributions to the anatomical sciences.
Ornitz Lab wins FASEB BioArt Competition (Again!) (Links to an external site)
Lu Yang (PhD student), Sung-Ho Huh (former postdoc), and David Ornitz (PI) are among the winners of the 2018 FASEB BioArt competition for their stunning image of the olfactory epithelium within the mouse nasal cavity. The Ornitz Lab also won in 2017 for their X-ray microscopy study showing blood flow in the lungs. Congrats!
New publication from Choi and Ornitz labs (Links to an external site)
Oladipupo, S.S., Kabir, A.U., Smith, C., Choi, K., Ornitz, D.M. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep, 8, 14724, 2018.
New paper from the Ornitz Lab (Links to an external site)
Yang LM, Huh S-H, Ornitz DM. FGF20-Expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Underlying Turbinate Growth to Optimize Surface Area. Dev Cell, 46: 564-580.e5, 2018.