Benjamin Humphreys, MD, PhD
Joseph Friedman Professor of Renal Diseases in Medicine, Division of Nephrology, Department of Medicine
- Email: email@example.com
Core Usage and WUSTL Affiliations:
- Genome Editing and iPSC Core (GEiC)
- Genome Technology Access Core (GTAC)
Selected Grants and Awards:
- American Society of Clinical Investigation
- ASN Gottschalk Research Scholar Award
- Re-Building a Kidney Consortium: NIDDK
- Chan Zuckerberg Initiative
Using stem cells to understand kidney development and disease
The Humphreys Lab is developing new and innovative treatments to help patients with kidney disease. They are using human stem cells to generate kidney organoids in a dish, with a goal of one day transplanting them into patients with kidney failure. They also study the kidney’s ability to regenerate itself so that they can harness this ability for therapeutic uses. The Humphreys lab has recently undertaken an ambitious project to single cell sequence the entire human kidney to understand all of the cell types that are present and their contributions to health, regeneration, and disease
Recent Publications and News
Proximal tubule translational profiling during kidney fibrosis reveals proinflammatory and long noncoding RNA expression patterns with sexual dimorphism (Links to an external site)
Wu, H., Lai, C.-F., Chang-Panesso, M., *Humphreys, B.D. Journal of the American Society of Nephrology, Volume 31: 23-38, 2020.
Prioritizing functional goals as we rebuild the kidney (Links to an external site)
*Humphreys, B.D., Knepper, M.A. JASN, Volume 30: 2287-2288, 2019.
The single-cell transcriptomic landscape of early human diabetic nephropathy (Links to an external site)
Wilson, P.C., Wu, H., Kirita, Y., (…), Waikar, S.S., *Humphreys, B.D. PNAS, 116(39), pp. 19619-19625, 2019.