Bailey, K.N., Furman, B.D., Zeitlin, J., (…), *Guilak, F., Olson, S.A. Osteoarthritis and CartilageVolume 28, Issue 5, May 2020, Pages 626-638.
Tag: Guilak
Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter (Links to an external site)
Dicks, A., Wu, C.-L., Steward, N., (…), Gersbach, C.A., *Guilak, F. Stem Cell Research and Therapy, Volume 11, Issue 1, 18 February 2020, Article number 66.
The role of macrophages in osteoarthritis and cartilage repair (Review) (Links to an external site)
Wu, C.-L., Harasymowicz, N.S., Klimak, M.A., Collins, K.H., *Guilak, F. Osteoarthritis and Cartilage, Volume 28: 544-554, 2020.
Single cell RNA-sequencing reveals cellular heterogeneity and trajectories of lineage specification during murine embryonic limb development (Links to an external site)
Kelly, N.H., Huynh, N.P.T., *Guilak, F. Matrix Biology, Volume 89, Pages 1-10 2020.
Proteomic analysis of synovial fluid identifies periostin as a biomarker for anterior cruciate ligament injury (Links to an external site)
Brophy, R.H., Cai, L., Duan, X., (…), *Guilak, F., *Rai, M.F. Osteoarthritis and Cartilage, 27:1778-1789, 2019.
Guilak lab postdoc receives K99/R00 from NIAMS
Chia-Lung Wu, a postdoc in Farsh Guilak’s lab, was awarded a highly-competitive K99/R00 from NIAMS to understand the epigenetic regulation of chondrogenesis during development and directed differentiation.
miR-892b Inhibits Hypertrophy by Targeting KLF10 in the Chondrogenesis of Mesenchymal Stem Cells (Links to an external site)
Lee, J.M., Ko, J.-Y., Kim, H.Y., (…), *Guilak, F., Im, G.-I. Molecular Therapy – Nucleic Acids, 17:310-322, 2019.
Journal of Orthopaedic Research: Special Issue on Stem Cells (Links to an external site)
*Guilak, F., *Sandell, L., Huard, J., 2019.
TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension (Links to an external site)
Gilchrist, C.L., Leddy, H.A., Kaye, L., (…), Hoffman, B.D., *Guilak, F. PNAS U S A, 116(6), pp. 1992-1997, 2019.
Guilak Lab paper (Links to an external site)
Harasymowicz, N.S., Dicks, A., Wu, C.-L., Guilak, F. Physiologic and pathologic effects of dietary free fatty acids on cells of the joint. Annals New York Acad Sci, 2019.
Review article from the Guilak Lab (Links to an external site)
Qu, F., Guilak, F., Mauck, R.L. Cell migration: implications for repair and regeneration in joint disease. Nat Rev Rheumatol, 2019.
CRM celebrates faculty accomplishments
On January 9th, the Center of Regenerative Medicine celebrated the successes of some of our faculty members. Promotion to associate professor with tenure (Grant Challen, Medicine; Spencer Lake, Mechanical Engineering; Andrew Yoo, Developmental Biology), promotion to full professor (Indira Mysorekar, Ob/Gyn), fellowship in the AAAS (Lila Solnica-Krezel, Developmental Biology and Deborah Rubin, Medicine), and installation […]
Guilak Lab publication (Links to an external site)
Venkatesan, J.K., Moutos, F.T., Rey-Rico, A., (…), Guilak, F., Cucchiarini, M. Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(∈-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer. Human Gene Ther, 29:1277-86, 2018.
New paper from the Guilak Lab (Links to an external site)
Adkar, S.S., Wu, C.-L., Willard, V.P., (…), Gersbach, C.A., Guilak, F. Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing. Stem Cells, 37:65-76, 2019.
New Guilak Lab publication (Links to an external site)
Adkar SS, Wu C-L, Willard VP, Dicks A, Ettyreddy A, Steward N, Bhutani N, Gersbach CA, Guilak F. Step‐Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR‐Cas9 Genome Editing. Stem Cells, online, 2018.
New paper from the Guilak Lab (Links to an external site)
Moffat, K.L., Goon, K., Moutos, F.T., (…), Zhao, X., Guilak, F. Composite Cellularized Structures Created from an Interpenetrating Polymer Network Hydrogel Reinforced by a 3D Woven Scaffold. Macromolecular Biosci, 18,1800140, 2018.
Guilak Lab publication (Links to an external site)
Huynh, N.P.T., Brunger, J.M., Gloss, C.C., (…), Gersbach, C.A., Guilak, F. Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds. Tiss Eng-Part A, 24:1531-44, 2018.
Two faculty members among the most highly-cited researchers (Links to an external site)
Farsh Guilak PhD (Orthopedic Surgery and CRM co-director) and David Curiel MD, PhD (Radiation Oncology) are among the world’s most highly-cited researchers, based on h-values as reported on their Google Scholar pages. Congrats!
Needleman Fellows in Regenerative Medicine Awarded to 4 Students
Congratulations to Lara Pferdehirt (Guilak Lab), Ali Ross (Guilak Lab), Yiran Hou (Wang Lab), and Ashraf Kabir (Choi Lab) on being named Philip and Sima Needleman Graduate Fellows in Regenerative Medicine! These awards are made possible though the generous support of Dr. and Mrs. Needleman. Megan Radyk (Mills Lab) and Bisi Fashemi (Mysorekar Lab) had […]
Podcast featuring Farsh Guilak is 4th most popular (Links to an external site)
A StemCellPodcast episode featuring the research of Dr. Farsh Guilak is the 4th most popular episode out of 126 episodes! Congrats to Dr. Guilak and his team.
Research from the Guilak lab featured in St. Louis Magazine (Links to an external site)
Research from CRM co-director Farsh Guilak’s lab was featured in an article in St. Louis Magazine about their strategies to use regenerative medicine to fight arthritis.