New paper from the Karch Lab

Jiang, S., Wen, N., Li, Z., (…), Cruchaga, C., Karch, C.M. Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. Transl Psych 8, art. no. 265, 2018.

New review article from the Karch Lab

Tavana, J.P., Rosene, M., Jensen, N.O., (…), Kauwe, J.S.K., Karch, C.M. RAB10: An alzheimer’s disease resilience locus and potential drug target. Clin Interventions Aging, 14:73-9, 2019.

Dr. Karch to lead collaborative neurodegeneration grant from CZI

Celeste Karch PhD (Psychiatry) was awarded a collaborative grant from the Chan Zuckerberg Initiative to study the role of TREM2 in Alzheimer’s Disease. This collaborative grant is part of the larger Neurodegeneration Challenge Network, and also features WUSTL faculty members Carlos Cruchaga, Gregory Day, and Oscar Harari.