Parker Harp, C.R., Archambault, A.S., Cheung, M., (…), *Randolph, G.J., Wu, G.F. PNAS, Volume 116: 24221-24230, 2019.
Category: Publications
Imaging in the repair of peripheral nerve injury (Links to an external site)
Luzhansky, I.D., Sudlow, L.C., *Brogan, D.M., *Wood, M.D., *Berezin, M.Y. Nanomedicine, Volume 14: 2659-2677, 2019.
Myocardial glucose and fatty acid metabolism is altered and associated with lower cardiac function in young adults with Barth syndrome (Links to an external site)
*Cade, W.T., Laforest, R., Bohnert, K.L., (…), Gropler, R.J., Peterson, L.R. Journal of Nuclear Cardiology, 2019.
A Metformin-Responsive Metabolic Pathway Controls Distinct Steps in Gastric Progenitor Fate Decisions and Maturation (Links to an external site)
Zhi-Feng Miao, Mahliyah Adkins-Threats, Joseph R. Burclaff, …, Zheng He, Zhen-Ning Wang, *Jason C. Mills. Cell Stem Cell, 26:1–16, 2020.
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development (Links to an external site)
Carissa Dege, Katherine H. Fegan, J. Philip Creamer, …, Todd A. Fehniger, James Palis, *Christopher M. Sturgeon. Dev Cell, 53:1–11, 2020.
Brown Fat Promotes Muscle Growth During Regeneration (Links to an external site)
Bryniarski, A.R., Meyer, G.A. Journal of Orthopaedic Research, 37(8), pp. 1817-1826, 2019.
DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration (Links to an external site)
Summers, D.W., Frey, E., Walker, L.J., *Milbrandt, J., *DiAntonio, A. Molecular Neurobiology, Volume 57, Issue 2, 1 February 2020, Pages 1146-1158, 2019.
Fat/Dachsous family cadherins in cell and tissue organisation (Links to an external site)
Fulford, A.D., *McNeill, H. Current Opinion in Cell Biology, 62, pp. 96-103, 2020.
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations (Links to an external site)
Dube, U., Del-Aguila, J.L., Li, Z., (…), *Karch, CM., Harari, O., Cruchaga, C. Nature Neuroscience, 22(11), pp. 1903-1912, 2019.
Cis-regulatory basis of sister cell type divergence in the vertebrate retina (Links to an external site)
Murphy, D.P., Hughes, A.E., Lawrence, K.A., Myers, C.A., *Corbo, J.C. eLife, Volume 8, October 2019, Article number e48216, 2019.
β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea (Links to an external site)
Jansson, L., Ebeid, M., Shen, J.W., (…), Huh, S.-H., Cheng, A.G. PNAS, 116(42), pp. 21054-21060, 2019.
DNA Damage Prediction Tool in Dilated Cardiomyopathy: Don’t Go Breaking My Heart (Links to an external site)
Jimenez, J., *Rentschler, S.L. JACC: Basic to Translational Science, 4(6), pp. 681-683, 2019.
Sodium-activated potassium channels moderate excitability in vascular smooth muscle (Links to an external site)
Li, P., Halabi, C.M., Stewart, R., (…), *Mecham, R.P., Salkoff, L. Journal of Physiology, 597(20), pp. 5093-5108, 2019.
Spatiotemporal delivery of basic fibroblast growth factor to directly and simultaneously attenuate cardiac fibrosis and promote cardiac tissue vascularization following myocardial infarction (Links to an external site)
Fan, Z., Xu, Z., Niu, H., (…), Ma, J., *Guan, J. Journal of Controlled Release, 311-312, pp. 233-244, 2019.
Platelet-Rich Plasma Released From Polyethylene Glycol Hydrogels Exerts Beneficial Effects on Human Chondrocytes (Links to an external site)
Jain, E., Chinzei, N., Blanco, A., (…), *Rai, M.F., Zustiak, S.P. Journal of orthopaedic research 37(11), pp. 2401-2410, 2019.
Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice (Links to an external site)
Yoshida, M., Satoh, A., Lin, J.B., (…), *Apte, R.S., *Imai, S.-I. Cell Metabolism, 30(2), pp. 329-342.e5, 2019.
Recent insights into the naïve state of human pluripotency and its applications (Links to an external site)
Dong, C., Fischer, L.A., *Theunissen, T.W. Experimental Cell Research, art. no. 111645, 2019.
Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target (Links to an external site)
Li, Y., Xu, Y., Benitez, B.A., (…), Crawford, B.E., *Sands, M.S. PNAS 116(40), pp. 20097-20103, 2019.
Ultra-low frequency labeling of single cell lineages in Drosophila (Links to an external site)
Snee, M., Lee, W.-C., Beehler-Evans, R., *Micchelli, C.A. Developmental Biology457:9-12, 2020.
Longer collagen fibers trigger multicellular streaming on soft substrates via enhanced forces and cell-cell cooperation (Links to an external site)
Sarker, B., Bagchi, A., Walter, C., Almeida, J., Pathak, A. Journal of Cell Science, 132(18), 2019.
Inhibition of 4-aminobutyrate aminotransferase protects against injury-induced osteoarthritis in mice (Links to an external site)
Shen, J., Wang, C., Ying, J., (…), *McAlinden, A., *O’Keefe, R.J. JCI Insight, 4(18), art. no. e128568, 2019.
The single-cell transcriptomic landscape of early human diabetic nephropathy (Links to an external site)
Wilson, P.C., Wu, H., Kirita, Y., (…), Waikar, S.S., *Humphreys, B.D. PNAS, 116(39), pp. 19619-19625, 2019.
Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota (Links to an external site)
Alvarado, D.M., Chen, B., Iticovici, M., (…), Tarr, P.I., *Ciorba, M.A. Gastroenterology, 157(4), pp. 1093-1108, 2019.
Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program (Links to an external site)
Geisler, S., Doan, R.A., Cheng, G.C., (…), *Milbrandt, J., *DiAntonio, A. JCI Insight, 4(17), art. no. e129920, 2019.
Proteomic analysis of synovial fluid identifies periostin as a biomarker for anterior cruciate ligament injury (Links to an external site)
Brophy, R.H., Cai, L., Duan, X., (…), *Guilak, F., *Rai, M.F. Osteoarthritis and Cartilage, 27:1778-1789, 2019.
Disrupted mechanobiology links the molecular and cellular phenotypes in familial dilated cardiomyopathy (Links to an external site)
Clippinger, S.R., Cloonan, P.E., Greenberg, L., (…), Stump, W.T., *Greenberg, M.J. PNAS, 116(36), pp. 17831-17840, 2019.
Skeletal muscle explants: ex-vivo models to study cellular behavior in a complex tissue environment (Links to an external site)
Smith, L.R., *Meyer, G.A. Connective Tissue Research, 2019.
A hydrogel platform for in vitro three dimensional assembly of human stem cell-derived islet cells and endothelial cells (Links to an external site)
Augsornworawat, P., Velazco-Cruz, L., Song, J., *Millman, J.R. Acta Biomaterialia 97:272-280, 2019.
Nomenclature for cellular plasticity: are the terms as plastic as the cells themselves? (Links to an external site)
*Mills, J.C., Stanger, B.Z., Sander, M. EMBO Journal, art. no. e103148, 2019.
Transcriptional profiling of intramembranous and endochondral ossification after fracture in mice (Links to an external site)
Coates, B.A., McKenzie, J.A., Buettmann, E.G., (…), *Zhang, B., *Silva, M.J. Bone, 127, pp. 577-591, 2019.
FGF2-induced STAT3 activation regulates pathologic neovascularization (Links to an external site)
Dong, Z., Santeford, A., Ban, N., (…), *Ornitz, D.M., *Apte, R.S. Experimental Eye Research, 187, art. no. 107775, 2019.
TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death (Links to an external site)
Wan, L., Essuman, K., Anderson, R.G., (…), *DiAntonio, A., *Milbrandt, J., Dangl, J.L., Nishimura, M.T. Science, 365(6455), pp. 799-803.
Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury (Links to an external site)
Meyer, A.R., Engevik, A.C., Willet, S.G., (…), *Mills, JC, Choi, E., Goldenring, J.R. Cellular and Molecular Gastroenterology and Hepatology, 8(3), pp. 379-405.
The cyclical hit model: How paligenosis might establish the mutational landscape in Barrett’s esophagus and esophageal adenocarcinoma (Links to an external site)
Jin, R.U., *Mills, J.C. Current Opinion in Gastroenterology, 35:363-370, 2019.
Current Landscape of Treatments for Wolfram Syndrome (Links to an external site)
Abreu, D., *Urano, F. Trends in Pharmacological Sciences40: 711-14, 2019.
Wnd/DLK Is a Critical Target of FMRP Responsible for Neurodevelopmental and Behavior Defects in the Drosophila Model of Fragile X Syndrome (Links to an external site)
Russo, A., DiAntonio, A. Cell Rep Volume 28, Issue 10, 3 September 2019, Pages 2581-2593.e5, 2019.
Immunological signatures in frontotemporal lobar degeneration (Links to an external site)
Sirkis, D.W., Bonham, L.W., *Karch, C.M., Yokoyama, J.S. Current Opinion in Neurology, 32(2), pp. 272-278, 2019.
Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers (Links to an external site)
Kedia, N., Arhzaouy, K., Pittman, S.K., (…), *Weihl, C.C., Bieschke, J., PNAS, Volume 116, Issue 34, 20 August 2019, Pages 16835-16840, 2019.
Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice (Links to an external site)
Seiler, K.M., Waye, S.E., Kong, W., (…), Warner, B.W., *Morris, S.A., Cell Mol Gastroenterol Hepatol, Volume 8, Issue 3, 2019, Pages 407-426, 2019.
Macrophage Plasticity and Function in the Eye and Heart (Links to an external site)
Wang, Z., Koenig, A.L., *Lavine, K.J., *Apte, R.S., Trends Immunol, Volume 40, Issue 9, September 2019, Pages 825-841, 2019.
Immunomodulatory role of nonneuronal cholinergic signaling in myocardial injury (Links to an external site)
Rocha-Resende, C., Weinheimer, C., Bajpai, G., (…), *Lavine, K.J., Mann, D.L., JCI Insight, Volume 4, Issue 14, 25 July 2019, Article number e128961, 2019.
An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis (Links to an external site)
Gertsman, I., Wuu, J., McAlonis-Downes, M., (…), *Miller, T.M., Da Cruz, S., JCI Insight, Volume 4, Issue 10, 2019, Article number e122768, 2019.
Zmym2 inhibits nanog-mediated reprogramming (Links to an external site)
Lawrence, M., *Theunissen, T.W., Lombard, P., Adams, D.J., Silva, J.C.R., Wellcome Open Res, Volume 4, 2019, Article number 88, 2019.
Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner (Links to an external site)
Yang, L.M., Cheah, K.S.E., Huh, S.-H., *Ornitz, D.M., PLoS Genetics, Volume 15, Issue 7, July 2019, Article number e1008254, 2019.
VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing (Links to an external site)
Buettmann, E.G., McKenzie, J.A., Migotsky, N., (…), Yoneda, S., Silva, M.J., J Bone Min Res, May 2019.
Transcriptional and Epigenetic Regulation of Cardiac Electrophysiology (Links to an external site)
Jimenez, J., Rentschler, S.L., Pediatric Cardiology, 2019
Generation and validation of novel conditional flox and inducible Cre alleles targeting fibroblast growth factor 18 (Fgf18) (Links to an external site)
Hagan, A.S., Boylan, M., Smith, C., (…), Lewandoski, M., Ornitz, D.M. Dev Dyn, 2019.
De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia (Links to an external site)
Undiagnosed Diseases Network (including *Schedl, TS, *Cole FF, and *Solnica-Krezel, L. Am J Hum Genet, 105:413-24, 2019.
Applications of RNA interference in the treatment of arthritis (Links to an external site)
*Rai, M.F., Pan, H., Yan, H., (…), Pham, C.T.N., Wickline, S.A. Translational Res, 2019.
Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice (Links to an external site)
Kim, J., Cocciolone, A.J., Staiculescu, M.C., *Mecham, R.P., *Wagenseil, J.E. Biomech Modeling Mechanobiol, 2019.