McKenzie, J.A., Maschhoff, C., Liu, X., (…), Silva, M.J., Gardner, M.J. Activation of hedgehog signaling by systemic agonist improves fracture healing in aged mice. J Ortho Res, 2018.
Category: Publications
New paper from the Humphreys and Morris Labs (Links to an external site)
Wu, H., Uchimura, K., Donnelly, E.L., (…), Morris, S.A., Humphreys, B.D. Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics. Cell Stem Cell, 23:869-81, 2018.
New paper from the Pathak Lab (Links to an external site)
Mathur, J., Sarker, B., Pathak, A. Predicting Collective Migration of Cell Populations Defined by Varying Repolarization Dynamics. Biophys J, 115:2474-85, 2018.
New publication from the Wang Lab (Links to an external site)
Keleher, M.R., Zaidi, R., Hicks, L., (…), Wang, T., Cheverud, J.M. A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice. BMC Genomics, 19:888, 2018.
New paper from the Huebsch Lab (Links to an external site)
Tveito, A., Jæger, K.H., Huebsch, N., (…), Wall, S., Healy, K.E. Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems. Sci Rep, 8:17626, 2018.
Guilak Lab publication (Links to an external site)
Venkatesan, J.K., Moutos, F.T., Rey-Rico, A., (…), Guilak, F., Cucchiarini, M. Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(∈-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer. Human Gene Ther, 29:1277-86, 2018.
New paper from Rai and Sandell Labs (Links to an external site)
Rai, M.F., Brophy, R.H., Sandell, L.J. Osteoarthritis following meniscus and ligament injury: insights from translational studies and animal models. Curr Opin Rheumatol, 31:70-79, 2019.
New paper from the Meyer Lab (Links to an external site)
Meyer GA. Evidence of induced muscle regeneration persists for years in the mouse. Muscle and Nerve, 58:858-862, 2018.
New Meyer Lab publication (Links to an external site)
Meyer, G., Lieber, R.L. Muscle fibers bear a larger fraction of passive muscle tension in frogs compared with mice. J Exp Biol, 221, 2018.
New paper from the DiPersio Lab (Links to an external site)
Alahmari, B., Cooper, M., Ziga, E., (…), DiPersio, J.F., Choi, J. Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation. PLoS One, 13, p.e0207609, 2018.
New Imai Lab paper
Johnson, S., Wozniak, D.F., Imai, S. CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves.npj Aging and Mechanisms of Disease, 4(1), art. no. 10, 2018.
New Schedl Lab publication (Links to an external site)
Kocsisova, Z., Mohammad, A., Kornfeld, K., Schedl, T. Cell Cycle Analysis in the C. elegans Germline with the Thymidine Analog EdU. JoVE, 140, 2018.
New paper from the Guilak Lab (Links to an external site)
Adkar, S.S., Wu, C.-L., Willard, V.P., (…), Gersbach, C.A., Guilak, F. Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing. Stem Cells, 37:65-76, 2019.
New paper from the Challen Lab (Links to an external site)
Celik, H., Koh, W.K., Kramer, A.C., (…), Oh, S.T., Challen, G.A. JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells. Cancer Cell 34:741-756.e8, 2018.
New paper from the Pascual-Garrido Lab (Links to an external site)
Rodriguez-Fontan, F., Piuzzi, N.S., Kraeutler, M.J., *Pascual-Garrido, C. Early Clinical Outcomes of Intra-Articular Injections of Bone Marrow Aspirate Concentrate for the Treatment of Early Osteoarthritis of the Hip, and Knee: A Cohort Study. PM&R, in press, 2018.
New paper from the Rai Lab (Links to an external site)
Brophy, R.H., Rothermich, M.A., Tycksen, E.D., Cai, L., Rai, M.F. Presence of meniscus tear alters gene expression profile of anterior cruciate ligament tears. J Ortho Res, 36:2612-21, 2018.
Perspective article from the Mokalled Lab (Links to an external site)
*Mokalled MH and Poss KD. A regeneration toolkit. Dev Cell, 47:267-80, 2018.
New publication from Mackinnon Lab (Links to an external site)
Fox, I.K., Novak, C.B., Krauss, E.M., (…), Winter, A.C., *Mackinnon, S.E. The Use of Nerve Transfers to Restore Upper Extremity Function in Cervical Spinal Cord Injury. PM&R, in press, 2018.
New Guilak Lab publication (Links to an external site)
Adkar SS, Wu C-L, Willard VP, Dicks A, Ettyreddy A, Steward N, Bhutani N, Gersbach CA, Guilak F. Step‐Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR‐Cas9 Genome Editing. Stem Cells, online, 2018.
Mills Lab review featuring Needleman Fellow (Links to an external site)
Burclaff J and Mills JC. Plasticity of differentiated cells in wound repair and tumorigenesis, part II: Skin and intestine. Disease Models Mechanisms, 11, dmm035071, 2018.
New paper from the Guilak Lab (Links to an external site)
Moffat, K.L., Goon, K., Moutos, F.T., (…), Zhao, X., Guilak, F. Composite Cellularized Structures Created from an Interpenetrating Polymer Network Hydrogel Reinforced by a 3D Woven Scaffold. Macromolecular Biosci, 18,1800140, 2018.
New review article from the Yoo Lab (Links to an external site)
Lu, Y.-L., Yoo, A.S. Mechanistic insights into MicroRNA-induced neuronal reprogramming of human adult fibroblasts. Frontiers Neurosci 12, 522, 2018.
New Miller Lab publication (Links to an external site)
Self, W.K., Schoch, K.M., Alex, J., (…), Bateman, R.J., Miller, T.M. Protein production is an early biomarker for RNA-targeted therapies. Ann Clin Transl Neurol, online, 2018.
New publication from Choi and Ornitz labs (Links to an external site)
Oladipupo, S.S., Kabir, A.U., Smith, C., Choi, K., Ornitz, D.M. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep, 8, 14724, 2018.
Guilak Lab publication (Links to an external site)
Huynh, N.P.T., Brunger, J.M., Gloss, C.C., (…), Gersbach, C.A., Guilak, F. Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds. Tiss Eng-Part A, 24:1531-44, 2018.
New publication from the Lake and Meyers labs (Links to an external site)
Dunham, C.L., Chamberlain, A.M., Meyer, G.A., Lake, S.P. Muscle does not drive persistent posttraumatic elbow contracture in a rat model. Muscle Nerve, online, 2018.
New Wang lab publication (Links to an external site)
Wang Y, Song F, Zhang B, (…), Wang T, Yue F. The 3D Genome Browser: A web-based browser for visualizing 3D genome organization and long-range chromatin interactions. Genome Biol. 19, 151, 2018.
Wang Lab publication (Links to an external site)
Zhang C, Lee HJ, Shrivastava A, (…), Pollok BA, Wang T. Long-Term In Vitro Expansion of Epithelial Stem Cells Enabled by Pharmacological Inhibition of PAK1-ROCK-Myosin II and TGF-β Signaling. Cell Rep, 25:598-610.e5
New paper from the Corbo Lab (Links to an external site)
Hughes AEO, Myers CA, Corbo JC. A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo. Genome Res, 28: 1520-31, 2018.
New paper from the Ornitz Lab (Links to an external site)
Yang LM, Huh S-H, Ornitz DM. FGF20-Expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Underlying Turbinate Growth to Optimize Surface Area. Dev Cell, 46: 564-580.e5, 2018.
New publication from Rentschler Lab (Links to an external site)
Li G, Khandekar A, Yin T, (…) and Rentschler SL. Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles. J Mol Cell Cardiol, 123:92-107, 2018.
New publication from Yang Lab (Links to an external site)
Yuan J, Zhang F, You M, and Yang Q. Identification of protein kinase inhibitors to reprogram breast cancer cells. Cell Death Disease, 9:915, 2018.
New publication from the Milbrandt Lab (Links to an external site)
Avey D, Sankararaman S, Kim AKY, Barve R, Milbrandt J, and Mitra RD. Single-Cell RNA-Seq Uncovers a Robust Transcriptional Response to Morphine by Glia. Cell Rep, 24:3619-3629.e4, 2018.
New publication from the Nerbonne Lab (Links to an external site)
Johnson EK, Matkovich SJ, and Nerbonne JM. Regional Differences in mRNA and lncRNA Expression Profiles in Non-Failing Human Atria and Ventricles. Sci Rep, 8:13919, 2018.
DiAntonio/Milbrandt Lab Publication featuring Needleman Fellow (Links to an external site)
Karney-Grobe S, Russo A, Frey E, Milbrandt J, and DiAntonio A. HSP90 is a chaperone for DLK and is required for axon injury signaling. PNAS, 2018.