Farners Amargant i Riera, PhD

Farners Amargant i Riera, PhD

Assistant Professor of Obstetrics & Gynecology

The Riera Lab uses a multidisciplinary approach to investigate how biochemical and biomechanical signaling from the ovary regulates folliculogenesis and oocyte quality, and whether these mechanisms are altered in reproductive-associated diseases such as PCOS and aging.

Riera Lab website »

Rajendra Apte, MD, PhD

Rajendra Apte, MD, PhD

Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences

Department of Ophthalmology and Visual Science

The Apte lab studies the molecular and cellular processes underlying neovascularization and cell degeneration in the retina.

 

Apte Lab website »

Luis Batista, PhD

Luis Batista, PhD

Assistant Professor

Division of Hematology, Department of Medicine

The Batista lab investigates the role of telomerase in stem cell function and regulation.

 

Batista Lab website »

 

 

Mikahil Berezin, PhD

Mikahil Berezin, PhD

Associate Professor, Radiology

Research in the Berezin lab is focused on peripheral nerve imaging and understanding the mechanism of chronic pain and peripheral nerve degeneration in cancer patients. They also work to design image guided grafts for nerve restoration.

Berezin Lab website »

Matthew Bersi, PhD

Matthew Bersi, PhD

Assistant Professor, Mechanical Engineering & Materials Science

The Bersi Lab uses experimental and computational approaches to better understand the relationship between biomechanics and inflammation in soft tissues. His group is focused on the role of the immune system in hypertension, cardiac fibrosis and vascular injury.
Thomas Brett, PhD

Thomas Brett, PhD

Associate Professor, Department of Medicine, Division of Pulmonary & Critical Care Medicine

The Brett Lab investigates the molecular mechanisms of chronic inflammatory lung disease and Alzheimer’s disease. We use structural, biophysical, model human tissues and complex cell co-culture models to investigate muco-obstructive diseases like cystic fibrosis and COPD. We also use structural, biophysical, and relevant human cellular models to investigate how microglial receptor-ligand interactions contribute to microglia function and neurodegeneration.

Brett Lab website »

David Brogan, MD

David Brogan, MD

Assistant Professor, Orthopedic Surgery

Dr. Brogan’s research focuses on peripheral nerve injury and regeneration, using stem cells and 3D printed scaffolds as therapies.

Faculty profile »

W. Todd Cade, PT, PhD

W. Todd Cade, PT, PhD

Professor

Program in Physical Therapy, Department of Medicine

The Cade lab investigates how nutritional factors influence cell behavior, and how iPSCs can be used to model human muscle diseases.

 

Alexendre R. Carter, MD, PhD

Alexendre R. Carter, MD, PhD

Associate Professor, Neurology

The Carter lab studies the mechanisms of neuroplasticity at the brain, spinal cord and peripheral levels.

 

 

Valeria Cavalli, PhD

Valeria Cavalli, PhD

Associate Professor

Department of Neuroscience

The Cavalli lab studies the molecular mechanisms of PNS injury signaling and axon regrowth, and how this can inform CNS regeneration.

 

Cavalli Lab website »

Grant Challen, PhD

Grant Challen, PhD

Associate Professor, Division of Oncology, Department of Medicine

The Challen lab focuses on how epigenetic marks regulate HSC self-renewal and differentiation, and how these are altered in lymphoma and leukemia.

 

Challen Lab website »

David Chen, MD, PhD

David Chen, MD, PhD

Assistant Professor, Department of Medicine, Division of Dermatology

The Chen Lab is interested in defining the genetic and epigenetic drivers of premalignant states in skin cancer.

Chen Lab Website »

Shiming Chen, PhD

Shiming Chen, PhD

Dr. Bernard and Janet R. Becker Distinguished Professor, Ophthalmology and Visual Sciences

The Chen Lab studies the molecular mechanisms controlling photoreceptor gene expression during photoreceptor development and maintenance in the mammalian retina, and how genetic mutations cause gene mis-regulation and defects in the function and survival of the photoreceptor neurons. They particularly focus on photoreceptor-specific transcription factors, such as CRX. Their ultimate goal is to develop therapeutic strategies for treatment.

 

Chen Lab website »

Yao Chen, PhD

Yao Chen, PhD

Assistant Professor, Department of Neuroscience

The Chen lab aims to understand how the dynamics of neuromodulators and intracellular signals contribute to the function of neuromodulators, to learning, and to the function of sleep. They hope to use organoids and stem cell models of probe these mechanisms.
Kyunghee Choi, PhD

Kyunghee Choi, PhD

Professor, Department of Pathology & Immunology

The Choi lab studies hematopoietic and endothelial development and the interplay between angiogenesis and immunity in cancer

 

Choi Lab website »

Brian Clark, PhD

Brian Clark, PhD

Assistant Professor, Ophthalmology and Visual Sciences

Using a suite of both moderate to high-throughput techniques in both mouse and zebrafish, the Clark Lab aims to identify the evolutionarily conserved and divergent pathways that regulate the temporally controlled specification of retinal cell fates.

 

Clark Lab website »

F. Sessions Cole, MD

F. Sessions Cole, MD

Park J. White M.D. Professor of Pediatrics

The Cole lab investigates the genetic mechanisms that underlie neonatal respiratory distress syndrome.

 

Faculty profile »

Joseph Corbo, MD, PhD

Joseph Corbo, MD, PhD

Professor

Department of Pathology and Immunology

The Corbo lab studies the transcriptional regulatory networks that underlie the development, evolution, and diseases of photoreceptors.

 

Corbo Lab website »

David Curiel, MD, PhD

David Curiel, MD, PhD

Professor

Department of Radiation Oncology

The Curiel lab studies how to engineer adenoviruses for cancer gene therapy.

 

Curiel Lab website »

Yifan Dai, PhD

Yifan Dai, PhD

Assistant Professor, Biomedical Engineering

The Dai Lab focuses on exploring the physical chemistry of biology to understand how chemical functions are encoded in biological soft matter. Their goal is to use fundamental capabilities of synthetic biology to design smart medicine capable of sensing and responding to cellular states for the improvement of human well-being.

Dai Lab website »

Nicholas Davidson, MD, Dsc

Nicholas Davidson, MD, Dsc

John E. and Adaline Simon Professor of Medicine and Division Chief of Gastroenterology

The Davidson Lab studies the role of gatekeeper genes that regulate intestinal and hepatic lipoprotein assembly and secretion, including apoB and microsomal triglyceride transfer protein (Mttp).

 

Faculty profile »

Aaron DiAntonio, MD, PhD

Aaron DiAntonio, MD, PhD

Alan A. and Edith L. Wolff Professor, Department of Developmental Biology

The DiAntonio lab studies the molecular mechanism that control axon generation, degeneration, and regeneration during development and disease.

 

DiAntonio Lab website »

Abhinav Diwan, MD

Abhinav Diwan, MD

Associate Professor, Division of Cardiology, Department of Medicine

The Diwan lab studies regulation of lysosome machinery in cardiometabolic diseases.

 

Diwan Lab website »

Nardhy Gomez-Lopez, PhD

Nardhy Gomez-Lopez, PhD

Professor of Obstetrics & Gynecology

The Gomez-Lopez Lab studies how disruption of immune pathways in pregnancy can lead to changes in fetal deveopment, the maternal fetal interface, and neonatal life.

Gomez-Lopez Lab website »

Farshid Guilak, PhD

Farshid Guilak, PhD

Co-Director, Center of Regenerative Medicine; Mildred B. Simon Professor of Orthopedic Surgery; Director of Research, Shriner's Hospitals - St. Louis

The Guilak Lab is pursuing a multidisciplinary approach to investigate the etiology and pathogenesis of osteoarthritis, as a basis for the development of new pharmacologic and stem cell therapies.

 

Guilak Lab website »

David Gutmann, MD, PhD

David Gutmann, MD, PhD

Donald O. Schnuck Family Professor & Vice Chair for Research Affairs

Department of Neurology

The Gutmann lab studies the cellular and molecular basis underlying nervous system dysfunction in neurofibromatosis using mouse and iPSC models.

 

Gutmann Lab website »

James Huettner, PhD

James Huettner, PhD

Professor, Cell Biology and Physiology

The Huettner lab studies how glutamate gated ion channels influence synapses and the differentiation of neurons from ES cells.

 

Faculty profile »

Benjamin Humphreys, MD, PhD

Benjamin Humphreys, MD, PhD

Joseph Friedman Professor of Renal Diseases in Medicine, Division of Nephrology, Department of Medicine

The Humphreys Lab develops new and innovative treatments to help patients with kidney disease. They are using human stem cells to generate kidney organoids in a dish, with a goal of one day transplanting them into patients with kidney failure. They also study the kidney’s ability to regenerate itself so that they can harness this ability for therapeutic uses.

 

Humphreys Lab website »

Shin-Ichiro Imai, MD, PhD

Shin-Ichiro Imai, MD, PhD

Professor, Developmental Biology

The Imai lab investigates the tissues, factors, and molecular mechanisms control mammalian aging.

 

Faculty profile »

Sanjay Jain, MD, PhD

Sanjay Jain, MD, PhD

Associate Professor, Division of Nephrology, Department of Medicine

The Jain lab studies the molecular and cellular mechanisms that regulate maintenance, differentiation and function of kidney progenitors in normal development and disease states.

 

Jain Lab website »

Sheng Chih (Peter) Jin, PhD

Sheng Chih (Peter) Jin, PhD

Assistant Professor, Department of Genetics

Research in the Jin lab is devoted to identifying the genes and elucidating the molecular, cellular, and developmental mechanisms that drive the development of specific neurodevelopmental disorders, including congenital hydrocephalus, cerebral palsy, and Moyamoya disease.

 

Jin Lab »

Aaron Johnson, PhD

Aaron Johnson, PhD

Assistant Professor, Developmental Biology

The Johnson lab studies the development and regeneration of muscle in fly and human.

 

Faculty profile »

Yoon-A Kang, PhD

Yoon-A Kang, PhD

Assistant Professor, Department of Medicine, Division of Hematology

The research interests of the Kang lab are understanding the mechanisms underlying cell fate decision and lineage specification in hematopoietic stem cells and multipotent progenitors to modulate lineage output in disease and aging contexts.

Kang lab website »

 

Celeste Karch, PhD

Celeste Karch, PhD

Associate Professor, Psychiatry

The Karch lab studies the molecular mechanisms underlying neurodegenerative tauopathies.

 

Karch Lab website »

Charles Kaufman, MD, PhD

Charles Kaufman, MD, PhD

Assistant Professor, Division of Oncology, Department of Medicine

The goal of the Kaufman lab is to understand how cells change their gene expression programs during normal development and cancer formation.

 

Kaufman Lab website »

Albert Kim, MD, PhD

Albert Kim, MD, PhD

Professor, Neurosurgery

The Kim Lab studies the cell-intrinsic molecular mechanisms governing brain cancer stem cell function, normal nervous system development, and the development of clinical surgical protocols to deliver cell-based and drug therapies for a variety of nervous system disorders.

 

Kim Lab website »

Kristen Kroll, PhD

Kristen Kroll, PhD

Professor, Developmental Biology

The Kroll lab studies the epigenetic and transcriptional regulators that control fate decisions from embryonic stem cells into the neural lineage.

 

Kroll Lab website »

Kory Lavine, MD, PhD

Kory Lavine, MD, PhD

Associate Professor, Division of Cardiology, Department of Medicine

The Lavine lab studies heart development and the role of macrophages in cardiac recovery and reprogramming.

 

Lavine Lab website »

Jin-Moo Lee, MD, PhD

Jin-Moo Lee, MD, PhD

Andrew B & Gretchen P Jones Professor. Chairman, Department of Neurology

The Lee Lab is engaged in translational research to investigate cellular and molecular mechanisms involved in acute and chronic brain injury, with a focus on ischemic stroke and Alzheimer’s disease.  An additional focus of the lab is neuroplasticity and brain repair after stroke.  A major motivation of the lab is to identify strategies and targets for mitigating brain injury and enhancing brain repair after injury. 

Lee Lab website »

Tristan Qingyun Li, PhD

Tristan Qingyun Li, PhD

Assistant Professor, Departments of Neuroscience and Genetics

The Li lab is broadly interested in neuroimmunology with a focus on microglial biology. They combine cutting-edge single-cell genomic technologies with in vitro and in vivo genetic, molecular, and cellular tools to address these fundamental questions, which also have tremendous translational potential. The overarching goal is to gain a better understanding of microglial functions in the establishment of the nervous system, as well as how changes in these functions contribute to aging and neurological diseases.

Li Lab website »

Susan Mackinnon, MD

Susan Mackinnon, MD

Sydney M. Jr. and Robert H. Shoenberg Professor and Chief, Division of Plastic and Reconstructive Surgery, Department of Surgery

The Mackinnon lab studies peripheral nerve allotransplantation and the effect of GDNF on nerve regeneration.

 

Faculty profile »

Audrey McAlinden, PhD

Audrey McAlinden, PhD

Associate Professor, Orthopedic Surgery

The McAlinden lab studies the molecular mechanisms regulating cartilage development and maintenance.

 

McAlinden Lab website »

Helen McNeill, PhD

Helen McNeill, PhD

Barnes Jewish Investigator and Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor of Developmental Biology

The McNeill Lab works on the roles of Fat cadherins in growth and regeneration, using Drosophila, mouse, and hydra.

 

McNeill Lab website »

Robert Mecham, PhD

Robert Mecham, PhD

Alumni Endowed Professor of Cell Biology and Physiology

The Mecham Lab studies how the extracellular matrix influences tissue development and regulates growth factor signaling.

 

Mecham Lab website »

Gretchen Meyer, PhD

Gretchen Meyer, PhD

Assistant Professor, Physical Therapy

The Meyer lab studies the effects of muscle injury at the molecular and tissue level and the role of adipose tissue in muscle repair.

 

Faculty profile »

Craig Micchelli, PhD

Craig Micchelli, PhD

Associate Professor, Developmental Biology

The Micchelli lab investigates the molecular mechanisms controlling Drosophila stem cell fate decisions, and how these can inform our understanding of all stem cell systems.

 

Faculty profile »

Jeffrey Milbrandt, MD, PhD

Jeffrey Milbrandt, MD, PhD

James S. McDonnell Professor and Head of Genetics

The Milbrandt lab studies mechanisms that influence axonal degeneration and regeneration.

 

Milbrandt Lab website »

Timothy Miller, MD, PhD

Timothy Miller, MD, PhD

The David Clayson Professor of Neurology

The Miller lab aims to understand the mechanisms underlying neurodegeneration and to develop novel therapies for neurodegenerative diseases, especially ALS.

 

Miller Lab website »

Jeffrey Millman, PhD

Jeffrey Millman, PhD

Associate Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine

The Millman lab investigates novel stem cell technology and biomedical engineering approaches for the treatment of diabetes.

 

Millman Lab website »

Mayssa Mokalled, PhD

Mayssa Mokalled, PhD

Assistant Professor, Developmental Biology

The Mokalled lab investigates mechanisms of spinal cord regeneration after injury or disease using zebrafish as a primary model.

 

Mokalled Lab website »