Associate Professor, Radiology
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Research in the Berezin lab is focused on peripheral nerve imaging and understanding the mechanism of chronic pain and peripheral nerve degeneration in cancer patients. They also work to design image guided grafts for nerve restoration.
Assistant Professor, Mechanical Engineering & Materials Science
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Associate Professor, Department of Medicine, Division of Pulmonary & Critical Care Medicine
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The Brett Lab investigates the molecular mechanisms of chronic inflammatory lung disease and Alzheimer’s disease. We use structural, biophysical, model human tissues and complex cell co-culture models to investigate muco-obstructive diseases like cystic fibrosis and COPD. We also use structural, biophysical, and relevant human cellular models to investigate how microglial receptor-ligand interactions contribute to microglia function and neurodegeneration.
Program in Physical Therapy, Department of Medicine
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The Cade lab investigates how nutritional factors influence cell behavior, and how iPSCs can be used to model human muscle diseases.
Associate Professor, Neurology
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The Carter lab studies the mechanisms of neuroplasticity at the brain, spinal cord and peripheral levels.
Dr. Bernard and Janet R. Becker Distinguished Professor, Ophthalmology and Visual Sciences
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The Chen Lab studies the molecular mechanisms controlling photoreceptor gene expression during photoreceptor development and maintenance in the mammalian retina, and how genetic mutations cause gene mis-regulation and defects in the function and survival of the photoreceptor neurons. They particularly focus on photoreceptor-specific transcription factors, such as CRX. Their ultimate goal is to develop therapeutic strategies for treatment.
Assistant Professor, Department of Neuroscience
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Assistant Professor, Ophthalmology and Visual Sciences
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Using a suite of both moderate to high-throughput techniques in both mouse and zebrafish, the Clark Lab aims to identify the evolutionarily conserved and divergent pathways that regulate the temporally controlled specification of retinal cell fates.
John E. and Adaline Simon Professor of Medicine and Division Chief of Gastroenterology
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The Davidson Lab studies the role of gatekeeper genes that regulate intestinal and hepatic lipoprotein assembly and secretion, including apoB and microsomal triglyceride transfer protein (Mttp).
Co-Director, Center of Regenerative Medicine; Mildred B. Simon Professor of Orthopedic Surgery; Director of Research, Shriner's Hospitals - St. Louis
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The Guilak Lab is pursuing a multidisciplinary approach to investigate the etiology and pathogenesis of osteoarthritis, as a basis for the development of new pharmacologic and stem cell therapies.
Joseph Friedman Professor of Renal Diseases in Medicine, Division of Nephrology, Department of Medicine
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The Humphreys Lab develops new and innovative treatments to help patients with kidney disease. They are using human stem cells to generate kidney organoids in a dish, with a goal of one day transplanting them into patients with kidney failure. They also study the kidney’s ability to regenerate itself so that they can harness this ability for therapeutic uses.
Assistant Professor, Department of Genetics
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Research in the Jin lab is devoted to identifying the genes and elucidating the molecular, cellular, and developmental mechanisms that drive the development of specific neurodevelopmental disorders, including congenital hydrocephalus, cerebral palsy, and Moyamoya disease.
Assistant Professor, Department of Medicine, Division of Hematology
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The research interests of the Kang lab are understanding the mechanisms underlying cell fate decision and lineage specification in hematopoietic stem cells and multipotent progenitors to modulate lineage output in disease and aging contexts.
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The Kim Lab studies the cell-intrinsic molecular mechanisms governing brain cancer stem cell function, normal nervous system development, and the development of clinical surgical protocols to deliver cell-based and drug therapies for a variety of nervous system disorders.
Andrew B & Gretchen P Jones Professor. Chairman, Department of Neurology
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The Lee Lab is engaged in translational research to investigate cellular and molecular mechanisms involved in acute and chronic brain injury, with a focus on ischemic stroke and Alzheimer’s disease. An additional focus of the lab is neuroplasticity and brain repair after stroke. A major motivation of the lab is to identify strategies and targets for mitigating brain injury and enhancing brain repair after injury.
Assistant Professor, Departments of Neuroscience and Genetics
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The Li lab is broadly interested in neuroimmunology with a focus on microglial biology. They combine cutting-edge single-cell genomic technologies with in vitro and in vivo genetic, molecular, and cellular tools to address these fundamental questions, which also have tremendous translational potential. The overarching goal is to gain a better understanding of microglial functions in the establishment of the nervous system, as well as how changes in these functions contribute to aging and neurological diseases.
Associate Professor of Genetics and of Developmental Biology
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The Morris lab studies the gene regulatory networks that define cell fate. This information is applied to engineer cell identity, and to better understand cell fate decisions in development and disease.
Alumni Endowed Professor of Developmental Biology and of Medicine, Division of Cardiology
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The Nerbonne lab studies the molecular mechanisms controlling the properties, the cell surface expression, and the function of voltage (K+) gated channels in the cardiovascular and nervous systems.