Jennifer Alexander-Brett, MD, PhD
Assistant Professor, Department of Medicine, Division of Pulmonary & Critical Care Medicine
- Email: jalexand@wustl.edu
The Alexander-Brett Lab integrates mucosal immunology, epithelial stem cell biology and protein biochemistry to investigate the role of stromal-immune intercellular crosstalk via extracellular vesicles in driving chronic lung disease pathogenesis.
David Alvarado
Assistant Professor, Surgery
- Email: alvaradodm@wustl.edu
My research focus is on the affect of human genetic variation on response to environmental stimuli, also known as gene-by-environment interactions. I am particularly interested in variants affecting the aryl hydrocarbon receptor (AHR) pathway in the development and progression of inflammatory bowel disease (IBD).
Farners Amargant i Riera, PhD
Assistant Professor of Obstetrics & Gynecology
- Email: farners@wustl.edu
The Riera Lab uses a multidisciplinary approach to investigate how biochemical and biomechanical signaling from the ovary regulates folliculogenesis and oocyte quality, and whether these mechanisms are altered in reproductive-associated diseases such as PCOS and aging.
Rajendra Apte, MD, PhD
Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences
Department of Ophthalmology and Visual Science
- Email: apte@vision.wustl.edu
The Apte lab studies the molecular and cellular processes underlying neovascularization and cell degeneration in the retina.
Ghazaleh Ashrafi
Assistant Professor, Cell Biology and Physiology, Genetics
- Email: ghazaleh@wustl.edu
The Ashrafi lab studies metabolic regulation of neurotransmission in health and in neurodegenerative diseases. To this end, the lab uses genetic, biochemical, and quantitative optical imaging techniques to probe metabolic and synaptic function in primary and stem cell-derived neurons and glial cells.
Luis Batista, PhD
Assistant Professor
Division of Hematology, Department of Medicine
- Email: LBATISTA@WUSTL.EDU
The Batista lab investigates the role of telomerase in stem cell function and regulation.
Philip Bayly, PhD
The Lilyan & E. Lisle Hughes Professor and Chair of Mechanical Engineering
Department of Mechanical Engineering and Materials Science
- Email: pvb@wustl.edu
The Bayly lab studies dynamic, mechanical phenomena in biomedical systems, including cortical folding and tissue mechanics in traumatic brain injury.
Mikahil Berezin, PhD
Associate Professor, Radiology
- Email: berezinm@wustl.edu
Research in the Berezin lab is focused on peripheral nerve imaging and understanding the mechanism of chronic pain and peripheral nerve degeneration in cancer patients. They also work to design image guided grafts for nerve restoration.
Matthew Bersi, PhD
Assistant Professor, Mechanical Engineering & Materials Science
- Email: mbersi@wustl.edu
Thomas Brett, PhD
Associate Professor, Department of Medicine, Division of Pulmonary & Critical Care Medicine
- Email: tbrett@wustl.edu
The Brett Lab investigates the molecular mechanisms of chronic inflammatory lung disease and Alzheimer’s disease. We use structural, biophysical, model human tissues and complex cell co-culture models to investigate muco-obstructive diseases like cystic fibrosis and COPD. We also use structural, biophysical, and relevant human cellular models to investigate how microglial receptor-ligand interactions contribute to microglia function and neurodegeneration.
David Brogan, MD
Assistant Professor, Orthopedic Surgery
- Email: brogand@wustl.edu
Dr. Brogan’s research focuses on peripheral nerve injury and regeneration, using stem cells and 3D printed scaffolds as therapies.
W. Todd Cade, PT, PhD
Professor
Program in Physical Therapy, Department of Medicine
- Email: tcade@wustl.edu
The Cade lab investigates how nutritional factors influence cell behavior, and how iPSCs can be used to model human muscle diseases.
Alexendre R. Carter, MD, PhD
Associate Professor, Neurology
- Email: alexandre.carter@wustl.edu
The Carter lab studies the mechanisms of neuroplasticity at the brain, spinal cord and peripheral levels.
Valeria Cavalli, PhD
Associate Professor
Department of Neuroscience
- Email: cavalli@wustl.edu
The Cavalli lab studies the molecular mechanisms of PNS injury signaling and axon regrowth, and how this can inform CNS regeneration.
Grant Challen, PhD
Associate Professor, Division of Oncology, Department of Medicine
- Email: grantchallen@wustl.edu
The Challen lab focuses on how epigenetic marks regulate HSC self-renewal and differentiation, and how these are altered in lymphoma and leukemia.
David Chen, MD, PhD
Assistant Professor, Department of Medicine, Division of Dermatology
- Email: davidchen@wustl.edu
The Chen Lab is interested in defining the genetic and epigenetic drivers of premalignant states in skin cancer.
Shiming Chen, PhD
Dr. Bernard and Janet R. Becker Distinguished Professor, Ophthalmology and Visual Sciences
- Email: chenshiming@wustl.edu
The Chen Lab studies the molecular mechanisms controlling photoreceptor gene expression during photoreceptor development and maintenance in the mammalian retina, and how genetic mutations cause gene mis-regulation and defects in the function and survival of the photoreceptor neurons. They particularly focus on photoreceptor-specific transcription factors, such as CRX. Their ultimate goal is to develop therapeutic strategies for treatment.
Yao Chen, PhD
Assistant Professor, Department of Neuroscience
- Email: yaochen@wustl.edu
Ying (Maggie) Chen
Associate Professor of Medicine, Division of Nephrology
- Email: ychen32@wustl.edu
Dr. Chen develops hiPSC-derived kidney organoids to model organelle stress-induced genetic kidney diseases and other innovative treatments.
Kyunghee Choi, PhD
Professor, Department of Pathology & Immunology
- Email: kchoi@wustl.edu
The Choi lab studies hematopoietic and endothelial development and the interplay between angiogenesis and immunity in cancer
Matthew Ciorba, MD
Associate Professor, Division of Gastroenterology, Department of Medicine
- Email: mciorba@wustl.edu
The Ciorba lab studies studies the roles of amino acid metabolism and microbial interactions in neoplastic and chronic inflammatory conditions of the GI tract.
Brian Clark, PhD
Assistant Professor, Ophthalmology and Visual Sciences
- Email: brian.s.clark@wustl.edu
Using a suite of both moderate to high-throughput techniques in both mouse and zebrafish, the Clark Lab aims to identify the evolutionarily conserved and divergent pathways that regulate the temporally controlled specification of retinal cell fates.
F. Sessions Cole, MD
Park J. White M.D. Professor of Pediatrics
- Email: fcole@wustl.edu
The Cole lab investigates the genetic mechanisms that underlie neonatal respiratory distress syndrome.
Joseph Corbo, MD, PhD
Professor
Department of Pathology and Immunology
- Email: jcorbo@wustl.edu
The Corbo lab studies the transcriptional regulatory networks that underlie the development, evolution, and diseases of photoreceptors.
Xiaoxia Cui, PhD
Associate Professor and Director, Genome Engineering & Stem Cell Center
- Email: x.cui@wustl.edu
Dr. Cui directs the Genome Engineering & Stem Cell Center at Washington University. The GESC’s mission is to empower its users with access to the most up-to-date technologies in the fields of gene editing and stem cells and enable the creation of research models best fit for the unique need of each lab.
Yifan Dai, PhD
Assistant Professor, Biomedical Engineering
- Email: dyifan@wustl.edu
The Dai Lab focuses on exploring the physical chemistry of biology to understand how chemical functions are encoded in biological soft matter. Their goal is to use fundamental capabilities of synthetic biology to design smart medicine capable of sensing and responding to cellular states for the improvement of human well-being.
Nicholas Davidson, MD, Dsc
John E. and Adaline Simon Professor of Medicine and Division Chief of Gastroenterology
- Email: nod@wustl.edu
The Davidson Lab studies the role of gatekeeper genes that regulate intestinal and hepatic lipoprotein assembly and secretion, including apoB and microsomal triglyceride transfer protein (Mttp).
Aaron DiAntonio, MD, PhD
Alan A. and Edith L. Wolff Professor, Department of Developmental Biology
- Email: diantonio@wustl.edu
The DiAntonio lab studies the molecular mechanism that control axon generation, degeneration, and regeneration during development and disease.
Sabine M Dietmann, PhD
Assistant Professor of Developmental Biology and Medicine, School of Medicine
- Email: sdietmann@wustl.edu
The Dietmann Lab specializes in the development of integrative multi-omics and machine learning approaches to the complex data sets generated by single-cell sequencing technologies in developmental biology and medicine. Her research has focused on the epigenetic landscape of embryonic stem cells and in vitro systems of human development. Of particular recent interest are studies of human organoids for applications in medicine and comparing developmental trajectories with other species and cell-cell communication.
John DiPersio, MD, PhD
Virginia E. & Sam J. Golman Professor of Medicine
Department of Medicine; Chief, Division of Oncology
- Email: jdipersi@wustl.edu
The DiPersio lab studies the mechanisms underlying leukemia, hematopoietic stem cell mobilization, and graft vs. host disease.
Naomi Dirckx
Assistant Professor, Orthopedic Surgery
- Email: dirckx@wustl.edu
My lab studies the role of the citrate transporter SLC13A5 in bone mineralization throughout growth and aging, as well as the systemic implications of altered citrate partitioning in skeletal tissues by targeting osteogenic citrate metabolism.
Abhinav Diwan, MD
Associate Professor, Division of Cardiology, Department of Medicine
- Email: adiwan@wustl.edu
The Diwan lab studies regulation of lysosome machinery in cardiometabolic diseases.
Nardhy Gomez-Lopez, PhD
Professor of Obstetrics & Gynecology
- Email: nardhy@wustl.edu
The Gomez-Lopez Lab studies how disruption of immune pathways in pregnancy can lead to changes in fetal deveopment, the maternal fetal interface, and neonatal life.
Michael Greenberg, PhD
Associate Professor, Biochemistry and Molecular Biophysics
- Email: greenberg@wustl.edu
The Greenberg lab studies familial cardiomyopathies, the leading cause of sudden cardiac death in young people, using an array of techniques, including stem cell technologies, tissue engineering, and genome editing.
Jianjun Guan, PhD
Professor, Mechanical Engineering and Materials Science
- Email: jguan22@wustl.edu
Research in the Guan Lab is focused on creating biomaterials for tissue regeneration and drug delivery.
Farshid Guilak, PhD
Co-Director, Center of Regenerative Medicine; Mildred B. Simon Professor of Orthopedic Surgery; Director of Research, Shriner’s Hospitals – St. Louis
- Email: guilak@wustl.edu
The Guilak Lab is pursuing a multidisciplinary approach to investigate the etiology and pathogenesis of osteoarthritis, as a basis for the development of new pharmacologic and stem cell therapies.
David Gutmann, MD, PhD
Donald O. Schnuck Family Professor & Vice Chair for Research Affairs
Department of Neurology
- Email: gutmannd@wustl.edu
The Gutmann lab studies the cellular and molecular basis underlying nervous system dysfunction in neurofibromatosis using mouse and iPSC models.
Claudia Han
Assistant Professor, Pathology and Immunology
- Email: claudiah@wustl.edu
We are interested in understanding the epigenetic mechanisms underlying the immune system’s contribution and response in neurodevelopmental and neurodegenerative diseases. We utilize both mouse and stem cell derived models.
Nathaniel Huebsch, PhD
Assistant Professor, Biomedical Engineering
- Email: nhuebsch@wustl.edu
Professor Huebsch’s research focus is in basic and translational stem cell mechanobiology, with specific focus on hydrogels to control cell-mediated tissue repair, and 3-D models heart-on-a-chip models derived from human induced pluripotent stem cells.
James Huettner, PhD
Professor, Cell Biology and Physiology
- Email: jhuettner@wustl.edu
The Huettner lab studies how glutamate gated ion channels influence synapses and the differentiation of neurons from ES cells.
Jing Hughes
Assistant Professor, Endocrinology
- Email: jing.hughes@wustl.edu
We study how the primary cilium, sensory antenna of the cell, regulates signaling and secretory functions in the pancreatic islet.
Benjamin Humphreys, MD, PhD
Joseph Friedman Professor of Renal Diseases in Medicine, Division of Nephrology, Department of Medicine
- Email: humphreysbd@wustl.edu
The Humphreys Lab develops new and innovative treatments to help patients with kidney disease. They are using human stem cells to generate kidney organoids in a dish, with a goal of one day transplanting them into patients with kidney failure. They also study the kidney’s ability to regenerate itself so that they can harness this ability for therapeutic uses.
Shin-Ichiro Imai, MD, PhD
Professor, Developmental Biology
- Email: imaishin@wustl.edu
The Imai lab investigates the tissues, factors, and molecular mechanisms control mammalian aging.
Sanjay Jain, MD, PhD
Associate Professor, Division of Nephrology, Department of Medicine
- Email: sanjayjain@wustl.edu
The Jain lab studies the molecular and cellular mechanisms that regulate maintenance, differentiation and function of kidney progenitors in normal development and disease states.
Sheng Chih (Peter) Jin, PhD
Assistant Professor, Department of Genetics
- Email: jin810@wustl.edu
Research in the Jin lab is devoted to identifying the genes and elucidating the molecular, cellular, and developmental mechanisms that drive the development of specific neurodevelopmental disorders, including congenital hydrocephalus, cerebral palsy, and Moyamoya disease.
Aaron Johnson, PhD
Assistant Professor, Developmental Biology
- Email: anjohnson@wustl.edu
The Johnson lab studies the development and regeneration of muscle in fly and human.
Yoon-A Kang, PhD
Assistant Professor, Department of Medicine, Division of Hematology
- Email: yoonakang@wustl.edu
The research interests of the Kang lab are understanding the mechanisms underlying cell fate decision and lineage specification in hematopoietic stem cells and multipotent progenitors to modulate lineage output in disease and aging contexts.
Celeste Karch, PhD
Associate Professor, Psychiatry
- Email: karchc@wustl.edu
The Karch lab studies the molecular mechanisms underlying neurodegenerative tauopathies.
Charles Kaufman, MD, PhD
Assistant Professor, Division of Oncology, Department of Medicine
- Email: ckkaufman@wustl.edu
The goal of the Kaufman lab is to understand how cells change their gene expression programs during normal development and cancer formation.
Peggy Kendall, MD
Professor and Chief, Division of Allergy and Immunology, Department of Medicine
- Email: peggy.kendall@wustl.edu
The Kendall Lab works on B Lymphocyte tolerance in autoimmune diseases, including Rheumatoid arthritis, Type 1 diabetes, and Systemic sclerosis. They also study allergic diseases, including food allergy.
Albert Kim, MD, PhD
Professor, Neurosurgery
- Email: kima@wustl.edu
The Kim Lab studies the cell-intrinsic molecular mechanisms governing brain cancer stem cell function, normal nervous system development, and the development of clinical surgical protocols to deliver cell-based and drug therapies for a variety of nervous system disorders.
Jinkyung Kim
Assistant Professor, Otolaryngology
- Email: jinkyung@wustl.edu
The Kim Lab is dedicated to understanding cochlear function at the cellular level and improving our ability to prevent hearing loss.
Miriam Kim
Assistant Professor, Oncology
- Email: miriamykim@wustl.edu
Focused research on rational manipulation of human hematopoietic cells for the treatment of disease by combining genetically engineered hematopoietic stem cells and chimeric antigen receptor T cells for therapy of acute myeloid leukemia.
Eynav Klechevsky
Associate Professor, Immunology
- Email: eklechevsky@wustl.edu
The Klechevsky Lab investigates the role of dendritic cell subsets in both healthy and diseased tissues, as well as the environmental cues that regulate their development, with the goal of developing novel immunotherapy approaches to combat cancer and autoimmune diseases.
Kristen Kroll, PhD
Professor, Developmental Biology
- Email: kkroll@wustl.edu
The Kroll lab studies the epigenetic and transcriptional regulators that control fate decisions from embryonic stem cells into the neural lineage.
Spencer Lake, PhD
Associate Professor, Mechanical Engineering and Materials Science
- Email: lake.s@wustl.edu
The Lake lab studies the biomechanics and structure-function relationships of soft tissues and how these change in injury and disease.
Kory Lavine, MD, PhD
Associate Professor, Division of Cardiology, Department of Medicine
- Email: klavine@wustl.edu
The Lavine lab studies heart development and the role of macrophages in cardiac recovery and reprogramming.
Jin-Moo Lee, MD, PhD
Andrew B & Gretchen P Jones Professor. Chairman, Department of Neurology
- Email: leejm@wustl.edu
The Lee Lab is engaged in translational research to investigate cellular and molecular mechanisms involved in acute and chronic brain injury, with a focus on ischemic stroke and Alzheimer’s disease. An additional focus of the lab is neuroplasticity and brain repair after stroke. A major motivation of the lab is to identify strategies and targets for mitigating brain injury and enhancing brain repair after injury.
Tristan Qingyun Li, PhD
Assistant Professor, Departments of Neuroscience and Genetics
- Email: qingyunli@wustl.edu
The Li lab is broadly interested in neuroimmunology with a focus on microglial biology. They combine cutting-edge single-cell genomic technologies with in vitro and in vivo genetic, molecular, and cellular tools to address these fundamental questions, which also have tremendous translational potential. The overarching goal is to gain a better understanding of microglial functions in the establishment of the nervous system, as well as how changes in these functions contribute to aging and neurological diseases.
Xiaowei Li, PhD
Assistant Professor, Department of Surgery, Division of Plastic Surgery
- Email: xiaoweili@wustl.edu
The Li lab is developing biomaterials platforms for regenerative medicine, with specific interest in applications of biomaterials for angiogenesis and vascularization, stem cell engineering, and central nervous system and soft tissue regeneration.
Susan Mackinnon, MD
Sydney M. Jr. and Robert H. Shoenberg Professor and Chief, Division of Plastic and Reconstructive Surgery, Department of Surgery
- Email: mackinnon@wudosis.wustl.edu
The Mackinnon lab studies peripheral nerve allotransplantation and the effect of GDNF on nerve regeneration.
Audrey McAlinden, PhD
Associate Professor, Orthopedic Surgery
- Email: mcalindena@wustl.edu
The McAlinden lab studies the molecular mechanisms regulating cartilage development and maintenance.
Helen McNeill, PhD
Barnes Jewish Investigator and Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor of Developmental Biology
- Email: mcneillh@wustl.edu
The McNeill Lab works on the roles of Fat cadherins in growth and regeneration, using Drosophila, mouse, and hydra.
Robert Mecham, PhD
Alumni Endowed Professor of Cell Biology and Physiology
- Email: bmecham@wustl.edu
The Mecham Lab studies how the extracellular matrix influences tissue development and regulates growth factor signaling.
Michael Meers, PhD
Assistant Professor, Department of Genetics
- Email: meers@wustl.edu
Isabel Menendez, DVM, PhD
Assistant Professor of Orthopedic Surgery
- Email: mimenendez@wustl.edu
Dr. Menendez uses preclinical multimodal imaging technologies for biomarker discovery in orthopedic diseases.
Gretchen Meyer, PhD
Assistant Professor, Physical Therapy
- Email: meyerg@wustl.edu
The Meyer lab studies the effects of muscle injury at the molecular and tissue level and the role of adipose tissue in muscle repair.
Craig Micchelli, PhD
Associate Professor, Developmental Biology
- Email: micchelli@wustl.edu
The Micchelli lab investigates the molecular mechanisms controlling Drosophila stem cell fate decisions, and how these can inform our understanding of all stem cell systems.
Jeffrey Milbrandt, MD, PhD
James S. McDonnell Professor and Head of Genetics
- Email: jmilbrandt@wustl.edu
The Milbrandt lab studies mechanisms that influence axonal degeneration and regeneration.
Timothy Miller, MD, PhD
The David Clayson Professor of Neurology
- Email: miller.t@wustl.edu
The Miller lab aims to understand the mechanisms underlying neurodegeneration and to develop novel therapies for neurodegenerative diseases, especially ALS.
Jeffrey Millman, PhD
Associate Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine
- Email: jmillman@wustl.edu
The Millman lab investigates novel stem cell technology and biomedical engineering approaches for the treatment of diabetes.
Sumegha Mitra, MS, PhD
Associate Professor of Obstetrics and Gynecology
- Email: smitra@wustl.edu
Dr. Mitra is focused on chemotherapy stress-induced mechanisms that provide resistance to endoplasmic reticulum stress and promote cell survival. She is also interested in regulating protein homeostasis to re-sensitize chemoresistant ovarian cancer to platinum drugs.
Mayssa Mokalled, PhD
Assistant Professor, Developmental Biology
- Email: mmokalled@wustl.edu
The Mokalled lab investigates mechanisms of spinal cord regeneration after injury or disease using zebrafish as a primary model.
Josh Morgan, PhD
Assistant Professor of Ophthalmology
- Email: jlmorgan@wustl.edu
The Morgan Lab studies the organization, development, degeneration, and regeneration of the synaptic organization of the visual system. We are currently focused on determining the extent to which microcircuitry in the visual thalamus can recover from denervation..
Samantha Morris, PhD
Associate Professor of Genetics and of Developmental Biology
- Email: s.morris@wustl.edu
The Morris lab studies the gene regulatory networks that define cell fate. This information is applied to engineer cell identity, and to better understand cell fate decisions in development and disease.
Jeffrey Neil, MD, PhD
Professor, Department of Neurology
- Email: neil@wustl.edu
The Neil lab specializes in the use of MRI methods to evaluate brain development in animal models and human infants.
Jeanne Nerbonne, PhD
Alumni Endowed Professor of Developmental Biology and of Medicine, Division of Cardiology
- Email: jnerbonne@wustl.edu
The Nerbonne lab studies the molecular mechanisms controlling the properties, the cell surface expression, and the function of voltage (K+) gated channels in the cardiovascular and nervous systems.
Regis O’Keefe, MD, PhD
Fred C. Reynolds Professor and Head of Orthopedic Surgery
- Email: okeefer@wustl.edu
The O’Keefe lab studies skeletal development and repair, cancer, and inflammatory diseases of bone.
Arin Oestreich
Assistant Professor of Orthopaedic Surgery
- Email: aoestreich@wustl.edu
Dr. Oestreich’s research focuses on how maternal obesity influences pregnancy health, fetal skeletal development, and the long term metabolic and musculoskeletal health of the adult offspring.
John A Olson Jr, MD, PhD
Chair, Department of Surgery, William K. Bixby Professor
The Olson laboratory investigates the molecular pathogenesis of parathyroid tumors with additional interests in parathyroid regeneration and transplantation. Clinical research within the Olson lab has focused on novel neoadjuvant therapies for breast cancer and biomarkers of breast cancer clinical outcomes.
David Ornitz, MD, PhD
Alumni Endowed Professor of Developmental Biology
- Email: dornitz@wustl.edu
The Ornitz lab investigates the functions of Fibroblast Growth Factors (FGFs), their interactions with other signaling pathways, and their role in tissue regeneration, response to injury, and cancer.
Michelle Oyen, PhD
Associate Professor, Biomedical Engineering
- Email: oyen@wustl.edu
Research in the Oyen Lab is focused on pregnancy and women’s health research, particularly in engineering approaches for prevention of and intervention into preterm birth.
B. Duygu Ozpolat, PhD
Assistant Professor, Department of Biology
- Email: bdozpolat@wustl.edu
If humans lose their reproductive cells (i.e eggs and sperm) they become infertile, in contrast, some animals regenerate their reproductive cells and reproductive organs. The Ozpolat lab’s goal is to uncover the mechanisms of reproductive cell and tissue regeneration by identifying the cell types and genes involved in this process, which will inform regenerative medicine approaches.
Hua Pan, PhD
Associate Professor, Department of Medicine
- Email: hpan@wustl.edu
The Pan Lab is studying the basic conception, development, and clinical application of novel nanostructures that serve as safe and effective delivery vehicles for therapeutic nucleotides to mitigate diseases including arthritis and cancer treatment induced vital organ injury.
Randal Paniello, MD, PhD
Professor, Otolaryngology
- Email: paniellor@wustl.edu
The Paniello lab is interested in using muscle stem cells to repair and treat vocal cord paralysis.
Rohit Pappu, PhD
Gene K. Beare Distinguished Professor of Biomedical Engineering
- Email: pappu@wustl.edu
The Pappu Lab studies the molecular basis of neurodegeneration, phase transitions that lead to protein and RNA condensates driven by multivalent molecules, the biophysics of intrinsically disordered proteins, and design of responsive, protein-based biomaterials. This includes multiscale computer simulations, adaptations and developments of polymer physics theories, in vitro experiments, and collaborations that enable molecular and cellular level investigations.
Cecilia Pascual-Garrido, MD
Assistant Professor, Orthopedic Surgery
- Email: cpascualgarrido@wustl.edu
Dr. Pascual-Garrido’s lab focuses on stem cell therapies for cartilage regeneration.
Amit Pathak, PhD
Associate Professor, Mechanical Engineering and Materials Science
- Email: pathaka@wustl.edu
The Pathak lab uses a multidisciplinary approach combining methods and concepts from biomaterials, microfluidics, molecular and cell biology, microscopy, applied mechanics, and computational modeling to investigate the ability of living cells to move through complex tissue environments.
Debabrata Patra, PhD
Associate Professor, Orthopedic Surgery
- Email: patrad@wudosis.wustl.edu
The Patra lab is interested in identifying and analyzing regulatory pathways that impact skeletal development. In particular, the lab is exploring roles for the proprotein convertase Site-1 protease (S1P) in cartilage, bone, and spine development.
Christine Pham, MD
Guy and Ella Mae Magness Professor of Medicine and Chief of Division of Rheumatology
- Email: cpham@wustl.edu
The Pham lab focuses on understanding the contribution of innate immunity to inflammatory and rheumatic diseases. They also develop nanomedicine and regenerative medicine approaches for the treatment of arthritis.
Elizabeth Pollina
Assistant Professor, Developmental Biology
- Email: pollina@wustl.edu
The Pollina lab leverages new tools and techniques from neuroscience, epigenetics, and genome integrity to advance our understanding of genome fidelity in the nervous system of living organisms. We characterize how diverse environmental stimuli trigger changes in transcription, chromatin, and DNA damage and examine how these dynamic processes go awry in aging and neurological disease.
M. Farooq Rai, PhD
Assistant Professor, Department of Orthopedic Surgery
- Email: rai.m@wustl.edu
Dr. Rai is interested in understanding the early molecular mechanisms that orchestrate changes in knee joint after injury and lead to the development of post-traumatic osteoarthritis.
Gwendalyn Randolph, PhD
Professor, Pathology and Immunology
- Email: GRandolph@path.wustl.edu
The Randolph Lab studies the development and diseases associated with monocytes, monocyte-derived cells, dendritic cells and vascular and lymphatic vessel biology.
Michael Rauchman, MDCM
Professor, Division of Nephrology, Department of Medicine
- Email: mrauchma@wustl.edu
Dr. Rauchman’s research focuses on understanding the molecular and genetic basis of mammalian kidney development, how disruption of specific pathways leads to abnormal development of this organ, the consequences of injury to adult kidney and the relationship between genetic mutations in humans and the development of future cardiovascular and renal disorders in humans.
Maria Remedi, PhD
Assistant Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine
- Email: mremedi@wustl.edu
The major focus of the Remedi laboratory is to study in vivo physiology in various mouse models of diabetes to unravel the underlying mechanisms of pancreatic β-cell failure and their consequences in both pancreatic and extra-pancreatic tissues.
Stacey Rentschler, MD, PhD
Associate Professor, Division of Cardiology, Department of Medicine
- Email: stacey.rentschler@wustl.edu
The Rentschler lab studies the molecular mechanisms of conduction cell specification and conductive disorders in heart biology.
Deborah Rubin, MD
William B. Kountz Professor of Medicine, Division of Gastroenterology, Department of Medicine
- Email: drubin@wustl.edu
The Rubin lab studies the molecular mechanisms underlying the regulation of intestinal epithelial cell proliferation, differentiation, and carcinogenesis.
David Rudnick, PhD
Associate Professor, Pediatrics
- Email: Rudnick_D@kids.wustl.edu
The Rudnick lab seeks to gain an understanding of liver regeneration to improve the treatment of children with liver disease.
Alexandra Rutz, PhD
Assistant Professor, Biomedical Engineering
- Email: rutzalexandral@wustl.edu
The Rutz lab is focused on bridging living systems and technologies through the design of materials and development of advanced manufacturing methods.