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Jennifer Alexander-Brett, MD, PhD

Jennifer Alexander-Brett, MD, PhD

Assistant Professor, Department of Medicine, Division of Pulmonary & Critical Care Medicine

The Alexander-Brett Lab integrates mucosal immunology, epithelial stem cell biology and protein biochemistry to investigate the role of stromal-immune intercellular crosstalk via extracellular vesicles in driving chronic lung disease pathogenesis.

Alexander-Brett Lab website »

Farners Amargant i Riera, PhD

Farners Amargant i Riera, PhD

Assistant Professor of Obstetrics & Gynecology

The Riera Lab uses a multidisciplinary approach to investigate how biochemical and biomechanical signaling from the ovary regulates folliculogenesis and oocyte quality, and whether these mechanisms are altered in reproductive-associated diseases such as PCOS and aging.

Riera Lab website »

Rajendra Apte, MD, PhD

Rajendra Apte, MD, PhD

Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences

Department of Ophthalmology and Visual Science

The Apte lab studies the molecular and cellular processes underlying neovascularization and cell degeneration in the retina.

 

Apte Lab website »

Luis Batista, PhD

Luis Batista, PhD

Assistant Professor

Division of Hematology, Department of Medicine

The Batista lab investigates the role of telomerase in stem cell function and regulation.

 

Batista Lab website »

 

 

Philip Bayly, PhD

Philip Bayly, PhD

The Lilyan & E. Lisle Hughes Professor and Chair of Mechanical Engineering

Department of Mechanical Engineering and Materials Science

The Bayly lab studies dynamic, mechanical phenomena in biomedical systems, including cortical folding and tissue mechanics in traumatic brain injury.

 

Bayly Lab website »

Mikahil Berezin, PhD

Mikahil Berezin, PhD

Associate Professor, Radiology

Research in the Berezin lab is focused on peripheral nerve imaging and understanding the mechanism of chronic pain and peripheral nerve degeneration in cancer patients. They also work to design image guided grafts for nerve restoration.

Berezin Lab website »

Matthew Bersi, PhD

Matthew Bersi, PhD

Assistant Professor, Mechanical Engineering & Materials Science

The Bersi Lab uses experimental and computational approaches to better understand the relationship between biomechanics and inflammation in soft tissues. His group is focused on the role of the immune system in hypertension, cardiac fibrosis and vascular injury.
Thomas Brett, PhD

Thomas Brett, PhD

Associate Professor, Department of Medicine, Division of Pulmonary & Critical Care Medicine

The Brett Lab investigates the molecular mechanisms of chronic inflammatory lung disease and Alzheimer’s disease. We use structural, biophysical, model human tissues and complex cell co-culture models to investigate muco-obstructive diseases like cystic fibrosis and COPD. We also use structural, biophysical, and relevant human cellular models to investigate how microglial receptor-ligand interactions contribute to microglia function and neurodegeneration.

Brett Lab website »

David Brogan, MD

David Brogan, MD

Assistant Professor, Orthopedic Surgery

Dr. Brogan’s research focuses on peripheral nerve injury and regeneration, using stem cells and 3D printed scaffolds as therapies.

Faculty profile »

W. Todd Cade, PT, PhD

W. Todd Cade, PT, PhD

Professor

Program in Physical Therapy, Department of Medicine

The Cade lab investigates how nutritional factors influence cell behavior, and how iPSCs can be used to model human muscle diseases.

 

Alexendre R. Carter, MD, PhD

Alexendre R. Carter, MD, PhD

Associate Professor, Neurology

The Carter lab studies the mechanisms of neuroplasticity at the brain, spinal cord and peripheral levels.

 

 

Valeria Cavalli, PhD

Valeria Cavalli, PhD

Associate Professor

Department of Neuroscience

The Cavalli lab studies the molecular mechanisms of PNS injury signaling and axon regrowth, and how this can inform CNS regeneration.

 

Cavalli Lab website »

Grant Challen, PhD

Grant Challen, PhD

Associate Professor, Division of Oncology, Department of Medicine

The Challen lab focuses on how epigenetic marks regulate HSC self-renewal and differentiation, and how these are altered in lymphoma and leukemia.

 

Challen Lab website »

David Chen, MD, PhD

David Chen, MD, PhD

Assistant Professor, Department of Medicine, Division of Dermatology

The Chen Lab is interested in defining the genetic and epigenetic drivers of premalignant states in skin cancer.

Chen Lab Website »

Shiming Chen, PhD

Shiming Chen, PhD

Dr. Bernard and Janet R. Becker Distinguished Professor, Ophthalmology and Visual Sciences

The Chen Lab studies the molecular mechanisms controlling photoreceptor gene expression during photoreceptor development and maintenance in the mammalian retina, and how genetic mutations cause gene mis-regulation and defects in the function and survival of the photoreceptor neurons. They particularly focus on photoreceptor-specific transcription factors, such as CRX. Their ultimate goal is to develop therapeutic strategies for treatment.

 

Chen Lab website »

Yao Chen, PhD

Yao Chen, PhD

Assistant Professor, Department of Neuroscience

The Chen lab aims to understand how the dynamics of neuromodulators and intracellular signals contribute to the function of neuromodulators, to learning, and to the function of sleep. They hope to use organoids and stem cell models of probe these mechanisms.
Kyunghee Choi, PhD

Kyunghee Choi, PhD

Professor, Department of Pathology & Immunology

The Choi lab studies hematopoietic and endothelial development and the interplay between angiogenesis and immunity in cancer

 

Choi Lab website »

Matthew Ciorba, MD

Matthew Ciorba, MD

Associate Professor, Division of Gastroenterology, Department of Medicine

The Ciorba lab studies studies the roles of amino acid metabolism and microbial interactions in neoplastic and chronic inflammatory conditions of the GI tract.

 

Ciorba Lab website »

Brian Clark, PhD

Brian Clark, PhD

Assistant Professor, Ophthalmology and Visual Sciences

Using a suite of both moderate to high-throughput techniques in both mouse and zebrafish, the Clark Lab aims to identify the evolutionarily conserved and divergent pathways that regulate the temporally controlled specification of retinal cell fates.

 

Clark Lab website »

F. Sessions Cole, MD

F. Sessions Cole, MD

Park J. White M.D. Professor of Pediatrics

The Cole lab investigates the genetic mechanisms that underlie neonatal respiratory distress syndrome.

 

Faculty profile »

Joseph Corbo, MD, PhD

Joseph Corbo, MD, PhD

Professor

Department of Pathology and Immunology

The Corbo lab studies the transcriptional regulatory networks that underlie the development, evolution, and diseases of photoreceptors.

 

Corbo Lab website »

Xiaoxia Cui, PhD

Xiaoxia Cui, PhD

Associate Professor and Director, Genome Engineering & Stem Cell Center

Dr. Cui directs the Genome Engineering & Stem Cell Center at Washington University. The GESC’s mission is to empower its users with access to the most up-to-date technologies in the fields of gene editing and stem cells and enable the creation of research models best fit for the unique need of each lab.

Genome Engineering & Stem Cell Center website »

David Curiel, MD, PhD

David Curiel, MD, PhD

Professor

Department of Radiation Oncology

The Curiel lab studies how to engineer adenoviruses for cancer gene therapy.

 

Curiel Lab website »

Yifan Dai, PhD

Yifan Dai, PhD

Assistant Professor, Biomedical Engineering

The Dai Lab focuses on exploring the physical chemistry of biology to understand how chemical functions are encoded in biological soft matter. Their goal is to use fundamental capabilities of synthetic biology to design smart medicine capable of sensing and responding to cellular states for the improvement of human well-being.

Dai Lab website »

Nicholas Davidson, MD, Dsc

Nicholas Davidson, MD, Dsc

John E. and Adaline Simon Professor of Medicine and Division Chief of Gastroenterology

The Davidson Lab studies the role of gatekeeper genes that regulate intestinal and hepatic lipoprotein assembly and secretion, including apoB and microsomal triglyceride transfer protein (Mttp).

 

Faculty profile »

Aaron DiAntonio, MD, PhD

Aaron DiAntonio, MD, PhD

Alan A. and Edith L. Wolff Professor, Department of Developmental Biology

The DiAntonio lab studies the molecular mechanism that control axon generation, degeneration, and regeneration during development and disease.

 

DiAntonio Lab website »

Sabine M Dietmann, PhD

Sabine M Dietmann, PhD

Assistant Professor of Developmental Biology and Medicine, School of Medicine

The Dietmann Lab specializes in the development of integrative multi-omics and machine learning approaches to the complex data sets generated by single-cell sequencing technologies in developmental biology and medicine. Her research has focused on the epigenetic landscape of embryonic stem cells and in vitro systems of human development. Of particular recent interest are studies of human organoids for applications in medicine and comparing developmental trajectories with other species and cell-cell communication. 

Dietmann Lab website »

John DiPersio, MD, PhD

John DiPersio, MD, PhD

Virginia E. & Sam J. Golman Professor of Medicine

Department of Medicine; Chief, Division of Oncology

The DiPersio lab studies the mechanisms underlying leukemia, hematopoietic stem cell mobilization, and graft vs. host disease.

 

DiPersio Lab website »

Abhinav Diwan, MD

Abhinav Diwan, MD

Associate Professor, Division of Cardiology, Department of Medicine

The Diwan lab studies regulation of lysosome machinery in cardiometabolic diseases.

 

Diwan Lab website »

Nardhy Gomez-Lopez, PhD

Nardhy Gomez-Lopez, PhD

Professor of Obstetrics & Gynecology

The Gomez-Lopez Lab studies how disruption of immune pathways in pregnancy can lead to changes in fetal deveopment, the maternal fetal interface, and neonatal life.

Gomez-Lopez Lab website »

Michael Greenberg, PhD

Michael Greenberg, PhD

Associate Professor, Biochemistry and Molecular Biophysics

The Greenberg lab studies familial cardiomyopathies, the leading cause of sudden cardiac death in young people, using an array of techniques, including stem cell technologies, tissue engineering, and genome editing.

 

Greenberg Lab website »

Jianjun Guan, PhD

Jianjun Guan, PhD

Professor, Mechanical Engineering and Materials Science

Research in the Guan Lab is focused on creating biomaterials for tissue regeneration and drug delivery.

 

Guan Lab website »

Farshid Guilak, PhD

Farshid Guilak, PhD

Co-Director, Center of Regenerative Medicine; Mildred B. Simon Professor of Orthopedic Surgery; Director of Research, Shriner’s Hospitals – St. Louis

The Guilak Lab is pursuing a multidisciplinary approach to investigate the etiology and pathogenesis of osteoarthritis, as a basis for the development of new pharmacologic and stem cell therapies.

 

Guilak Lab website »

David Gutmann, MD, PhD

David Gutmann, MD, PhD

Donald O. Schnuck Family Professor & Vice Chair for Research Affairs

Department of Neurology

The Gutmann lab studies the cellular and molecular basis underlying nervous system dysfunction in neurofibromatosis using mouse and iPSC models.

 

Gutmann Lab website »

Nathaniel Huebsch, PhD

Nathaniel Huebsch, PhD

Assistant Professor, Biomedical Engineering

Professor Huebsch’s research focus is in basic and translational stem cell mechanobiology, with specific focus on hydrogels to control cell-mediated tissue repair, and 3-D models heart-on-a-chip models derived from human induced pluripotent stem cells.

 

Faculty profile »

James Huettner, PhD

James Huettner, PhD

Professor, Cell Biology and Physiology

The Huettner lab studies how glutamate gated ion channels influence synapses and the differentiation of neurons from ES cells.

 

Faculty profile »

Benjamin Humphreys, MD, PhD

Benjamin Humphreys, MD, PhD

Joseph Friedman Professor of Renal Diseases in Medicine, Division of Nephrology, Department of Medicine

The Humphreys Lab develops new and innovative treatments to help patients with kidney disease. They are using human stem cells to generate kidney organoids in a dish, with a goal of one day transplanting them into patients with kidney failure. They also study the kidney’s ability to regenerate itself so that they can harness this ability for therapeutic uses.

 

Humphreys Lab website »

Shin-Ichiro Imai, MD, PhD

Shin-Ichiro Imai, MD, PhD

Professor, Developmental Biology

The Imai lab investigates the tissues, factors, and molecular mechanisms control mammalian aging.

 

Faculty profile »

Sanjay Jain, MD, PhD

Sanjay Jain, MD, PhD

Associate Professor, Division of Nephrology, Department of Medicine

The Jain lab studies the molecular and cellular mechanisms that regulate maintenance, differentiation and function of kidney progenitors in normal development and disease states.

 

Jain Lab website »

Sheng Chih (Peter) Jin, PhD

Sheng Chih (Peter) Jin, PhD

Assistant Professor, Department of Genetics

Research in the Jin lab is devoted to identifying the genes and elucidating the molecular, cellular, and developmental mechanisms that drive the development of specific neurodevelopmental disorders, including congenital hydrocephalus, cerebral palsy, and Moyamoya disease.

 

Jin Lab »

Aaron Johnson, PhD

Aaron Johnson, PhD

Assistant Professor, Developmental Biology

The Johnson lab studies the development and regeneration of muscle in fly and human.

 

Faculty profile »

Yoon-A Kang, PhD

Yoon-A Kang, PhD

Assistant Professor, Department of Medicine, Division of Hematology

The research interests of the Kang lab are understanding the mechanisms underlying cell fate decision and lineage specification in hematopoietic stem cells and multipotent progenitors to modulate lineage output in disease and aging contexts.

Kang lab website »

 

Celeste Karch, PhD

Celeste Karch, PhD

Associate Professor, Psychiatry

The Karch lab studies the molecular mechanisms underlying neurodegenerative tauopathies.

 

Karch Lab website »

Charles Kaufman, MD, PhD

Charles Kaufman, MD, PhD

Assistant Professor, Division of Oncology, Department of Medicine

The goal of the Kaufman lab is to understand how cells change their gene expression programs during normal development and cancer formation.

 

Kaufman Lab website »

Peggy Kendall, MD

Peggy Kendall, MD

Professor and Chief, Division of Allergy and Immunology, Department of Medicine

The Kendall Lab works on B Lymphocyte tolerance in autoimmune diseases, including Rheumatoid arthritis, Type 1 diabetes, and Systemic sclerosis. They also study allergic diseases, including food allergy.

Kendall Lab website »

Albert Kim, MD, PhD

Albert Kim, MD, PhD

Professor, Neurosurgery

The Kim Lab studies the cell-intrinsic molecular mechanisms governing brain cancer stem cell function, normal nervous system development, and the development of clinical surgical protocols to deliver cell-based and drug therapies for a variety of nervous system disorders.

 

Kim Lab website »

Kristen Kroll, PhD

Kristen Kroll, PhD

Professor, Developmental Biology

The Kroll lab studies the epigenetic and transcriptional regulators that control fate decisions from embryonic stem cells into the neural lineage.

 

Kroll Lab website »

Spencer Lake, PhD

Spencer Lake, PhD

Associate Professor, Mechanical Engineering and Materials Science

The Lake lab studies the biomechanics and structure-function relationships of soft tissues and how these change in injury and disease.

 

Lake Lab website »

Kory Lavine, MD, PhD

Kory Lavine, MD, PhD

Associate Professor, Division of Cardiology, Department of Medicine

The Lavine lab studies heart development and the role of macrophages in cardiac recovery and reprogramming.

 

Lavine Lab website »

Jin-Moo Lee, MD, PhD

Jin-Moo Lee, MD, PhD

Andrew B & Gretchen P Jones Professor. Chairman, Department of Neurology

The Lee Lab is engaged in translational research to investigate cellular and molecular mechanisms involved in acute and chronic brain injury, with a focus on ischemic stroke and Alzheimer’s disease.  An additional focus of the lab is neuroplasticity and brain repair after stroke.  A major motivation of the lab is to identify strategies and targets for mitigating brain injury and enhancing brain repair after injury. 

Lee Lab website »

Tristan Qingyun Li, PhD

Tristan Qingyun Li, PhD

Assistant Professor, Departments of Neuroscience and Genetics

The Li lab is broadly interested in neuroimmunology with a focus on microglial biology. They combine cutting-edge single-cell genomic technologies with in vitro and in vivo genetic, molecular, and cellular tools to address these fundamental questions, which also have tremendous translational potential. The overarching goal is to gain a better understanding of microglial functions in the establishment of the nervous system, as well as how changes in these functions contribute to aging and neurological diseases.

Li Lab website »

Xiaowei Li, PhD

Xiaowei Li, PhD

Assistant Professor, Department of Surgery, Division of Plastic Surgery

The Li lab is developing biomaterials platforms for regenerative medicine, with specific interest in applications of biomaterials for angiogenesis and vascularization, stem cell engineering, and central nervous system and soft tissue regeneration.

Li Lab website »

Susan Mackinnon, MD

Susan Mackinnon, MD

Sydney M. Jr. and Robert H. Shoenberg Professor and Chief, Division of Plastic and Reconstructive Surgery, Department of Surgery

The Mackinnon lab studies peripheral nerve allotransplantation and the effect of GDNF on nerve regeneration.

 

Faculty profile »

Audrey McAlinden, PhD

Audrey McAlinden, PhD

Associate Professor, Orthopedic Surgery

The McAlinden lab studies the molecular mechanisms regulating cartilage development and maintenance.

 

McAlinden Lab website »

Helen McNeill, PhD

Helen McNeill, PhD

Barnes Jewish Investigator and Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor of Developmental Biology

The McNeill Lab works on the roles of Fat cadherins in growth and regeneration, using Drosophila, mouse, and hydra.

 

McNeill Lab website »

Robert Mecham, PhD

Robert Mecham, PhD

Alumni Endowed Professor of Cell Biology and Physiology

The Mecham Lab studies how the extracellular matrix influences tissue development and regulates growth factor signaling.

 

Mecham Lab website »

Michael Meers, PhD

Michael Meers, PhD

Assistant Professor, Department of Genetics

The Meers Lab studies how transcription factors interact with and overcome barriers presented by chromatin landscapes to specify developmental and cellular reprogramming outcomes. To do so, we develop cutting-edge epigenomics techniques to map transcription factor binding and chromatin structure in the same context at high resolution.
Isabel Menendez, DVM, PhD

Isabel Menendez, DVM, PhD

Assistant Professor of Orthopedic Surgery

Dr. Menendez uses preclinical multimodal imaging technologies for biomarker discovery in orthopedic diseases.

Faculty profile website »

Gretchen Meyer, PhD

Gretchen Meyer, PhD

Assistant Professor, Physical Therapy

The Meyer lab studies the effects of muscle injury at the molecular and tissue level and the role of adipose tissue in muscle repair.

 

Faculty profile »

Craig Micchelli, PhD

Craig Micchelli, PhD

Associate Professor, Developmental Biology

The Micchelli lab investigates the molecular mechanisms controlling Drosophila stem cell fate decisions, and how these can inform our understanding of all stem cell systems.

 

Faculty profile »

Jeffrey Milbrandt, MD, PhD

Jeffrey Milbrandt, MD, PhD

James S. McDonnell Professor and Head of Genetics

The Milbrandt lab studies mechanisms that influence axonal degeneration and regeneration.

 

Milbrandt Lab website »

Timothy Miller, MD, PhD

Timothy Miller, MD, PhD

The David Clayson Professor of Neurology

The Miller lab aims to understand the mechanisms underlying neurodegeneration and to develop novel therapies for neurodegenerative diseases, especially ALS.

 

Miller Lab website »

Jeffrey Millman, PhD

Jeffrey Millman, PhD

Associate Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine

The Millman lab investigates novel stem cell technology and biomedical engineering approaches for the treatment of diabetes.

 

Millman Lab website »

Sumegha Mitra, MS, PhD

Sumegha Mitra, MS, PhD

Associate Professor of Obstetrics and Gynecology

Dr. Mitra is focused on chemotherapy stress-induced mechanisms that provide resistance to endoplasmic reticulum stress and promote cell survival. She is also interested in regulating protein homeostasis to re-sensitize chemoresistant ovarian cancer to platinum drugs.

Mitra Lab website »

Mayssa Mokalled, PhD

Mayssa Mokalled, PhD

Assistant Professor, Developmental Biology

The Mokalled lab investigates mechanisms of spinal cord regeneration after injury or disease using zebrafish as a primary model.

 

Mokalled Lab website »

Josh Morgan, PhD

Josh Morgan, PhD

Assistant Professor of Ophthalmology

The Morgan Lab studies the organization, development, degeneration, and regeneration of the synaptic organization of the visual system. We are currently focused on determining the extent to which microcircuitry in the visual thalamus can recover from denervation..

Morgan Lab website »

Samantha Morris, PhD

Samantha Morris, PhD

Associate Professor of Genetics and of Developmental Biology

The Morris lab studies the gene regulatory networks that define cell fate. This information is applied to engineer cell identity, and to better understand cell fate decisions in development and disease.

 

Morris Lab website »

Jeffrey Neil, MD, PhD

Jeffrey Neil, MD, PhD

Professor, Department of Neurology

The Neil lab specializes in the use of MRI methods to evaluate brain development in animal models and human infants.

Neil Lab website »

Jeanne Nerbonne, PhD

Jeanne Nerbonne, PhD

Alumni Endowed Professor of Developmental Biology and of Medicine, Division of Cardiology

The Nerbonne lab studies the molecular mechanisms controlling the properties, the cell surface expression, and the function of voltage (K+) gated channels in the cardiovascular and nervous systems.

 

Nerbonne Lab website »

Regis O'Keefe, MD, PhD

Regis O’Keefe, MD, PhD

Fred C. Reynolds Professor and Head of Orthopedic Surgery

The O’Keefe lab studies skeletal development and repair, cancer, and inflammatory diseases of bone.

 

O’Keefe Lab website »

Arin Oestreich

Arin Oestreich

Assistant Professor of Orthopaedic Surgery

Dr. Oestreich’s research focuses on how maternal obesity influences pregnancy health, fetal skeletal development, and the long term metabolic and musculoskeletal health of the adult offspring.

Faculty profile website »

John A Olson Jr, MD, PhD

John A Olson Jr, MD, PhD

Chair, Department of Surgery, William K. Bixby Professor

The Olson laboratory investigates the molecular pathogenesis of parathyroid tumors with additional interests in parathyroid regeneration and transplantation. Clinical research within the Olson lab has focused on novel neoadjuvant therapies for breast cancer and biomarkers of breast cancer clinical outcomes.

Olson Lab website »

David Ornitz, MD, PhD

David Ornitz, MD, PhD

Alumni Endowed Professor of Developmental Biology

The Ornitz lab investigates the functions of Fibroblast Growth Factors (FGFs), their interactions with other signaling pathways, and their role in tissue regeneration, response to injury, and cancer.

 

Ornitz Lab website »

Michelle Oyen, PhD

Michelle Oyen, PhD

Associate Professor, Biomedical Engineering

Research in the Oyen Lab is focused on pregnancy and women’s health research, particularly in engineering approaches for prevention of and intervention into preterm birth.

 

Oyen Lab website »

B. Duygu Ozpolat, PhD

B. Duygu Ozpolat, PhD

Assistant Professor, Department of Biology

If humans lose their reproductive cells (i.e eggs and sperm) they become infertile, in contrast, some animals regenerate their reproductive cells and reproductive organs. The Ozpolat lab’s goal is to uncover the mechanisms of reproductive cell and tissue regeneration by identifying the cell types and genes involved in this process, which will inform regenerative medicine approaches.

Ozpolat lab website »

Hua Pan, PhD

Hua Pan, PhD

Associate Professor, Department of Medicine

The Pan Lab is studying the basic conception, development, and clinical application of novel nanostructures that serve as safe and effective delivery vehicles for therapeutic nucleotides to mitigate diseases including arthritis and cancer treatment induced vital organ injury.

Pan Lab website »

Randal Paniello, MD, PhD

Randal Paniello, MD, PhD

Professor, Otolaryngology

The Paniello lab is interested in using muscle stem cells to repair and treat vocal cord paralysis.

 

Paniello Lab website »

Rohit Pappu, PhD

Rohit Pappu, PhD

Gene K. Beare Distinguished Professor of Biomedical Engineering

The Pappu Lab studies the molecular basis of neurodegeneration, phase transitions that lead to protein and RNA condensates driven by multivalent molecules, the biophysics of intrinsically disordered proteins, and design of responsive, protein-based biomaterials. This includes multiscale computer simulations, adaptations and developments of polymer physics theories, in vitro experiments, and collaborations that enable molecular and cellular level investigations.

Pappu Lab website »

Cecilia Pascual-Garrido, MD

Cecilia Pascual-Garrido, MD

Assistant Professor, Orthopedic Surgery

Dr. Pascual-Garrido’s lab focuses on stem cell therapies for cartilage regeneration.

 

Pascual-Garrdio Lab website »

Amit Pathak, PhD

Amit Pathak, PhD

Associate Professor, Mechanical Engineering and Materials Science

The Pathak lab uses a multidisciplinary approach combining methods and concepts from biomaterials, microfluidics, molecular and cell biology, microscopy, applied mechanics, and computational modeling to investigate the ability of living cells to move through complex tissue environments.

 

Pathak Lab website »

Debabrata Patra, PhD

Debabrata Patra, PhD

Associate Professor, Orthopedic Surgery

The Patra lab is interested in identifying and analyzing regulatory pathways that impact skeletal development. In particular, the lab is exploring roles for the proprotein convertase Site-1 protease (S1P) in cartilage, bone, and spine development.

Christine Pham, MD

Christine Pham, MD

Guy and Ella Mae Magness Professor of Medicine and Chief of Division of Rheumatology

The Pham lab focuses on understanding the contribution of innate immunity to inflammatory and rheumatic diseases. They also develop nanomedicine and regenerative medicine approaches for the treatment of arthritis.

 

Faculty profile »

M. Farooq Rai, PhD

M. Farooq Rai, PhD

Assistant Professor, Department of Orthopedic Surgery

Dr. Rai is interested in understanding the early molecular mechanisms that orchestrate changes in knee joint after injury and lead to the development of post-traumatic osteoarthritis.

Gwendalyn Randolph, PhD

Gwendalyn Randolph, PhD

Professor, Pathology and Immunology

The Randolph Lab studies the development and diseases associated with monocytes, monocyte-derived cells, dendritic cells and vascular and lymphatic vessel biology.

 

Randolph Lab website »

Michael Rauchman, MDCM

Michael Rauchman, MDCM

Professor, Division of Nephrology, Department of Medicine

Dr. Rauchman’s research focuses on understanding the molecular and genetic basis of mammalian kidney development, how disruption of specific pathways leads to abnormal development of this organ, the consequences of injury to adult kidney and the relationship between genetic mutations in humans and the development of future cardiovascular and renal disorders in humans.

 

Faculty profile »

Maria Remedi, PhD

Maria Remedi, PhD

Assistant Professor; Division of Endocrinology, Metabolism, and Lipid Research; Department of Medicine

The major focus of the Remedi laboratory is to study in vivo physiology in various mouse models of diabetes to unravel the underlying mechanisms of pancreatic β-cell failure and their consequences in both pancreatic and extra-pancreatic tissues.

 

Remedi Lab website »

Stacey Rentschler, MD, PhD

Stacey Rentschler, MD, PhD

Associate Professor, Division of Cardiology, Department of Medicine

The Rentschler lab studies the molecular mechanisms of conduction cell specification and conductive disorders in heart biology.

 

Faculty profile »

Deborah  Rubin, MD

Deborah Rubin, MD

William B. Kountz Professor of Medicine, Division of Gastroenterology, Department of Medicine

The Rubin lab studies the molecular mechanisms underlying the regulation of intestinal epithelial cell proliferation, differentiation, and carcinogenesis.

 

Faculty profile »

David Rudnick, PhD

David Rudnick, PhD

Associate Professor, Pediatrics

The Rudnick lab seeks to gain an understanding of liver regeneration to improve the treatment of children with liver disease.

 

Faculty profile »

Alexandra  Rutz, PhD

Alexandra Rutz, PhD

Assistant Professor, Biomedical Engineering

The Rutz lab is focused on bridging living systems and technologies through the design of materials and development of advanced manufacturing methods.

 

Rutz Lab »

Mark Sands, PhD

Mark Sands, PhD

Professor, Division of Oncology, Department of Medicine

The Sands lab studies the underlying pathophysiology of lysosomal storage diseases and develops therapies to treat them.

 

Faculty profile »

Timothy Schedl, PhD

Timothy Schedl, PhD

Professor, Genetics

The Schedl lab investigates how stem cells choose between self renewal and differentiation and how sex determination is controlled.

 

Schedl Lab website »

Erica L Scheller, DDS, PhD

Erica L Scheller, DDS, PhD

Executive Director, Center of Regenerative Medicine; Assistant Professor of Medicine; Assistant Professor of Cell Biology and Physiology

The Scheller laboratory synthesizes concepts from cell biology, physiology, and bioengineering to study the relationships between the nervous system and the skeleton. They have a directed interest in understanding how neural signals contribute to skeletal homeostasis, and how perturbations to this system contribute to bone loss, impaired healing, and altered regeneration. They also seek to understand how skeletal cells and proteins coordinate and regulate nerve regeneration in and on the bone.

Scheller Lab website »

Laura Schuettpelz, MD, PhD

Laura Schuettpelz, MD, PhD

Associate Professor, Pediatrics

The Schuettpelz lab studies how inflammatory signals regulate hematopoietic stem cells.

 

Schuettpelz Lab website »

Lori Setton, PhD

Lori Setton, PhD

Lucy & Stanley Lopata Distinguished Professor and Chair of Biomedical Engineering

The Setton Lab focuses on engineering and design of novel materials and drug depots to support regeneration of tissues of the musculoskeletal system.

 

Setton Lab website »

Lavinia Sheets, PhD

Lavinia Sheets, PhD

Assistant Professor, Otolaryngology

The Sheets lab uses zebrafish as a model system to understand how senory hair cells of the auditory system develop, degenerate, and regenerate. A main focus of the lab is to identify biological pathways that promote nerve regeneration and hair-cell reinnervation with the goal of providing information toward clinical regenerative therapies.

 

Sheets Lab website »

Hua  Shen, PhD

Hua Shen, PhD

Instructor, Orthopedic Surgery

Dr. Shen’s group studies biological and mechanical factors that regulate tendon development, injury, and repair, as a basis to develop new therapeutic approaches to improve tendon healing.

 

Jie Shen, PhD

Jie Shen, PhD

Assistant Professor, Orthopedic Surgery

The Shen laboratory recently works on epigenetics of degenerative and regenerative processes in the muscuoskeletal system, e.g. osteoarthritis and bony fracture. They employ unbiased approaches to study the genomic and epigenomic alterations in skeletal diseases.

Matthew Silva, PhD

Matthew Silva, PhD

Julia and Walter R. Peterson Orthopaedic Research Professor, Orthopedic Surgery

The Silva lab studies the mechanical and molecular factors that regulate loading-induced bone formation and bone injury response and repair.

Jim Skeath, PhD

Jim Skeath, PhD

Professor, Genetics

The Skeath lab investigatesthe genetic and molecular basis of both asymmetric divisions and cell-type specific differentiation programs through the use of the Drosophila model system, focusing primarily on nervous system development.

 

Skeath Lab website »